The ATPase Reaction Cycle of Yeast DNA Topoisomerase II

DNA topoisomerase II catalyzes the transport of one DNA duplex through a transient break in a second duplex using a complex ATP hydrolysis mechanism. Two key rates in the ATPase mechanism, ATP resynthesis and phosphate release, were investigated using 18 O exchange and stopped-flow phosphate release...

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Bibliographic Details
Published inThe Journal of biological chemistry Vol. 276; no. 30; pp. 27893 - 27898
Main Authors Baird, Cheryl L., Gordon, Matthew S., Andrenyak, David M., Marecek, James F., Lindsley, Janet E.
Format Journal Article
LanguageEnglish
Published American Society for Biochemistry and Molecular Biology 27.07.2001
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