From structure to function: A comprehensive overview of polysaccharide roles and applications
Abstract Polysaccharides, also known as glycans, are biological macromolecules consisting of many monosaccharide units. Alongside proteins, nucleic acids, and lipids, they constitute the four fundamental substances crucial for life activities and essential for the growth and development of living or...
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| Published in | Food frontiers |
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| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
25.09.2024
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| Online Access | Get full text |
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| Abstract | Abstract Polysaccharides, also known as glycans, are biological macromolecules consisting of many monosaccharide units. Alongside proteins, nucleic acids, and lipids, they constitute the four fundamental substances crucial for life activities and essential for the growth and development of living organisms. As natural products with inherent biological activity, polysaccharides are widely available, nontoxic, and possess numerous functional properties, holding immense potential for advancement in food, medicine, and cosmetics. Furthermore, the exploration of polysaccharide‐based drugs, as an alternative to conventional therapies, emerges as a promising avenue for addressing future disease challenges. This article comprehensively reviews the sources, structural characteristics, synthesis, degradation, functions, and applications of polysaccharides. The potential of polysaccharides for pharmacological applications, in antitumor, antiaging, antioxidant, hypoglycemic, anti‐inflammatory, antiviral, and anticoagulant properties, is summarized. Additionally, the role of polysaccharides in environmental protection is discussed. It is anticipated that this review will offer innovative strategic insights, serving as a theoretical foundation and inspiration for the subsequent research on polysaccharides in healthcare. |
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| AbstractList | Abstract Polysaccharides, also known as glycans, are biological macromolecules consisting of many monosaccharide units. Alongside proteins, nucleic acids, and lipids, they constitute the four fundamental substances crucial for life activities and essential for the growth and development of living organisms. As natural products with inherent biological activity, polysaccharides are widely available, nontoxic, and possess numerous functional properties, holding immense potential for advancement in food, medicine, and cosmetics. Furthermore, the exploration of polysaccharide‐based drugs, as an alternative to conventional therapies, emerges as a promising avenue for addressing future disease challenges. This article comprehensively reviews the sources, structural characteristics, synthesis, degradation, functions, and applications of polysaccharides. The potential of polysaccharides for pharmacological applications, in antitumor, antiaging, antioxidant, hypoglycemic, anti‐inflammatory, antiviral, and anticoagulant properties, is summarized. Additionally, the role of polysaccharides in environmental protection is discussed. It is anticipated that this review will offer innovative strategic insights, serving as a theoretical foundation and inspiration for the subsequent research on polysaccharides in healthcare. |
| Author | Li, Sai‐sai Ding, Wen‐li Wang, Li Zhang, Cai Huang, Shu‐cheng Rehman, Mujeeb Ur Tareen, Muhammad Farooq Xu, Bo‐wen |
| Author_xml | – sequence: 1 givenname: Bo‐wen surname: Xu fullname: Xu, Bo‐wen organization: College of Veterinary Medicine Henan Agricultural University Zhengzhou China – sequence: 2 givenname: Sai‐sai surname: Li fullname: Li, Sai‐sai organization: College of Veterinary Medicine South China Agricultural University Guangzhou China – sequence: 3 givenname: Wen‐li surname: Ding fullname: Ding, Wen‐li organization: College of Veterinary Medicine Henan Agricultural University Zhengzhou China – sequence: 4 givenname: Cai surname: Zhang fullname: Zhang, Cai organization: Henan International Joint Laboratory of Animal Welfare and Health Breeding Henan University of Science and Technology Luoyang China – sequence: 5 givenname: Mujeeb Ur surname: Rehman fullname: Rehman, Mujeeb Ur organization: Directorate Planning & Development Livestock & Dairy Development Department Balochistan Quetta Pakistan – sequence: 6 givenname: Muhammad Farooq surname: Tareen fullname: Tareen, Muhammad Farooq organization: Directorate Planning & Development Livestock & Dairy Development Department Balochistan Quetta Pakistan – sequence: 7 givenname: Li surname: Wang fullname: Wang, Li organization: Department of Traditional Chinese Medicine, College of Agronomy Henan Agricultural University Zhengzhou China – sequence: 8 givenname: Shu‐cheng orcidid: 0000-0003-3163-8616 surname: Huang fullname: Huang, Shu‐cheng organization: College of Veterinary Medicine Henan Agricultural University Zhengzhou China |
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| Title | From structure to function: A comprehensive overview of polysaccharide roles and applications |
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