347 Histopathology of Necrotic Spinal Cord Tissue Exudate Collected During Surgical Implantation of a Biodegradable Scaffold Following Acute Spinal Cord Injury: Pre-clinical and Clinical Findings

• Published in: Neurosurgery Vol. 64; no. CN_suppl_1; pp. 278 - 279
• Main Authors: Lee, K Stuart, Boyer, Philip J, Hsieh, Patrick C, Hurth, Kyle M, Guest, James D, Aimetti, Alex, Layer, Richard T, Moore, Simon W, Ulich, Thomas
• Format: Journal Article
• Language: English
• Published: Philadelphia Oxford University Press 01.09.2017; Copyright by the Congress of Neurological Surgeons; Wolters Kluwer Health, Inc
• Subjects: Spinal cord injuries

Abstract INTRODUCTION Acute implantation of biodegradable scaffolds following spinal cord injury (SCI) has been shown pre-clinically to reduce chronic cavitation, increase white matter sparing, and increase the deposition of neuropermissive remodeled tissue. The surgical procedure of scaffold implan...