Neutrophilic Extracellular Traps (NETs); A Subset of Smudge Cells Identifiable by Peripheral Smear Autoanalyzers in the Rising Era of Artificial Intelligence

• Published in: American journal of clinical pathology Vol. 154; no. Supplement_1; pp. S10 - S11
• Main Authors: Barouqa, Mohammad, Ikemura, Kenji, Billett, Henny, Kushnir, Margarita, Fedorov, Kateryna, Yin, David, Gil, Morayma Reyes
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 28.10.2020
• Subjects: 12-O-Tetradecanoylphorbol-13-acetate; Acetic acid; Alkaline phosphatase; Artificial intelligence; Blood; Chromatin; Citrulline; Cytology; Degranulation; Demography; Elastase; Flow cytometry; Hematology; Heme; Histones; Immunofluorescence; Immunohistochemistry; Immunoproliferative diseases; Infections; Ionomycin; Leukocytes (neutrophilic); Leukocytosis; Lipopolysaccharides; Lymphocytes; Morphology; Neural networks; Neutrophils; Patients; Statistical analysis

Abstract Background Digitized microscopy such as CellaVision® technology has revolutionized the laboratory. Smudge cells, also called basket cells, are usually seen in lymphoproliferative disorders representing remnants from degenerated lymphocytes (DLs). CellaVision® classifies DLs and web-like rem...