O papel da avaliação inicial simplificada no prognóstico da pancreatite aguda

OBJETIVO: Correlacionar a avaliação clínico-laboratorial inicial simplificada com a gravidade da pancreatite aguda e a presença de necrose. MÉTODO: Foi realizado um estudo retrospectivo dos pacientes com diagnóstico final de PA internados no Hospital Universitário Clementino Fraga Filho - UFRJ entre...

Full description

Saved in:
Bibliographic Details
Published inRevista do Colégio Brasileiro de Cirurgiões Vol. 33; no. 3; pp. 161 - 168
Main Authors Carneiro, Márcio Cavalcante, Manso, José Eduardo Ferreira, Eulálio, José Marcus Raso, Renteria, Juan Miguel, Costa, Mariana Dias
Format Journal Article
LanguageEnglish
Published 01.06.2006
Online AccessGet full text
ISSN0100-6991
0100-6991
DOI10.1590/S0100-69912006000300007

Cover

Loading…
Abstract OBJETIVO: Correlacionar a avaliação clínico-laboratorial inicial simplificada com a gravidade da pancreatite aguda e a presença de necrose. MÉTODO: Foi realizado um estudo retrospectivo dos pacientes com diagnóstico final de PA internados no Hospital Universitário Clementino Fraga Filho - UFRJ entre janeiro de 1990 e agosto de 2002. Foi considerado apenas o primeiro episódio de cada paciente. Os dados obtidos foram submetidos a análise estatística. Foram estudados 164 pacientes onde a idade média foi de 43,7 anos. RESULTADOS: A etiologia biliar foi a mais freqüente com 43,9% dos casos. A incidência de necrose foi de 21,3% e a mortalidade global de 23,2%. Observamos que a ausência de taquicardia na admissão estava associada à forma branda da doença, e que os níveis plasmáticos de uréia e creatinina elevados na admissão estão associados à forma grave da doença, e a hiperglicemia (121mg/dl) à necrose pancreática. CONCLUSÕES: A avaliação inicial simplificada ainda tem espaço, embora que limitado, no acompanhamento do paciente com PA. BACKGROUND: Our goal was to study if early and simplified clinical and laboratorial evaluation are associated to severity and necrosis in acute panceatitis (AP). METHODS: One hundred and sixty four patients, hospitalized at the Clementino Fraga Filho University Hospital between January 1990 and August 2002 with a AP final diagnosis, were included in this study. The study was retrospective and included only the first episode of each patient. From the charts we obtained clinical, laboratorial, imaging exams, operations and death data. From these data we established the severity of each case. Statistical analysis used the Variance Analysis test of Kruskal-Wallis, completed by the Multiple Comparisons test if the diference was significant. Statistic significance was defined as p< 0,05. RESULTS: Biliar etiology was the most common: 43,9% of cases, necrosis incidence was 21,3% and overall mortality was 23,2%. We observed that normal cardiac frequency at admission was associated to mild AP, as high urea and creatinine plasmatic levels at admission to severe AP, and hyperglycemia (121 mg/dl) to pancreatic necrosis. CONCLUSION: We concluded that early and simplified clinical and laboratorial evaluation at admission had a limited but clear role in AP prognosis.
AbstractList OBJETIVO: Correlacionar a avaliação clínico-laboratorial inicial simplificada com a gravidade da pancreatite aguda e a presença de necrose. MÉTODO: Foi realizado um estudo retrospectivo dos pacientes com diagnóstico final de PA internados no Hospital Universitário Clementino Fraga Filho - UFRJ entre janeiro de 1990 e agosto de 2002. Foi considerado apenas o primeiro episódio de cada paciente. Os dados obtidos foram submetidos a análise estatística. Foram estudados 164 pacientes onde a idade média foi de 43,7 anos. RESULTADOS: A etiologia biliar foi a mais freqüente com 43,9% dos casos. A incidência de necrose foi de 21,3% e a mortalidade global de 23,2%. Observamos que a ausência de taquicardia na admissão estava associada à forma branda da doença, e que os níveis plasmáticos de uréia e creatinina elevados na admissão estão associados à forma grave da doença, e a hiperglicemia (121mg/dl) à necrose pancreática. CONCLUSÕES: A avaliação inicial simplificada ainda tem espaço, embora que limitado, no acompanhamento do paciente com PA. BACKGROUND: Our goal was to study if early and simplified clinical and laboratorial evaluation are associated to severity and necrosis in acute panceatitis (AP). METHODS: One hundred and sixty four patients, hospitalized at the Clementino Fraga Filho University Hospital between January 1990 and August 2002 with a AP final diagnosis, were included in this study. The study was retrospective and included only the first episode of each patient. From the charts we obtained clinical, laboratorial, imaging exams, operations and death data. From these data we established the severity of each case. Statistical analysis used the Variance Analysis test of Kruskal-Wallis, completed by the Multiple Comparisons test if the diference was significant. Statistic significance was defined as p< 0,05. RESULTS: Biliar etiology was the most common: 43,9% of cases, necrosis incidence was 21,3% and overall mortality was 23,2%. We observed that normal cardiac frequency at admission was associated to mild AP, as high urea and creatinine plasmatic levels at admission to severe AP, and hyperglycemia (121 mg/dl) to pancreatic necrosis. CONCLUSION: We concluded that early and simplified clinical and laboratorial evaluation at admission had a limited but clear role in AP prognosis.
Author Manso, José Eduardo Ferreira
Costa, Mariana Dias
Renteria, Juan Miguel
Eulálio, José Marcus Raso
Carneiro, Márcio Cavalcante
Author_xml – sequence: 1
  givenname: Márcio Cavalcante
  surname: Carneiro
  fullname: Carneiro, Márcio Cavalcante
  organization: Hospital Municipal Souza Aguiar; Faculdade de Medicina de Teresópolis; UFRJ
– sequence: 2
  givenname: José Eduardo Ferreira
  surname: Manso
  fullname: Manso, José Eduardo Ferreira
  organization: UFRJ; UFRJ; Hospital Municipal da Piedade
– sequence: 3
  givenname: José Marcus Raso
  surname: Eulálio
  fullname: Eulálio, José Marcus Raso
  organization: UFRJ; UFRJ
– sequence: 4
  givenname: Juan Miguel
  surname: Renteria
  fullname: Renteria, Juan Miguel
  organization: UFRJ
– sequence: 5
  givenname: Mariana Dias
  surname: Costa
  fullname: Costa, Mariana Dias
  organization: UFRJ
BookMark eNqFkE1KA0EQhRuJYBI9g32B0arp-eleuJDgHwQiqOuh0tMTWibdQ_coeB4XHsAj5GJOoojowkXxCl59RdWbsJHzzjB2jHCCuYLTO0CApFAKU4ACAMRQUO6x8bcx-tEfsEmMjwCZQCXG7HbBO-pMy2vi9Eytpc3b5tVz66y21PJo111rG6tpGHCed8Gv3OY99lb7LdOR08FQb3vDafVU0yHbb6iN5uhLp-zh8uJ-dp3MF1c3s_N5ojHHMpFZhqXIJNQqU0LIZZPmqUTRFHm-RIMoUYqMTD4YNYKqEZfSQLHTdLh-ysrPvTr4GINpqi7YNYWXCqHaBlPtgqn-BDOQZ79IbfvhA-_6QLb9l_8ASeNqzA
CitedBy_id crossref_primary_10_1590_S0100_69912012000500008
Cites_doi 10.1159/000055817
10.1016/S0039-6109(05)70039-6
10.1097/00004836-200202000-00014
10.1001/archsurg.135.11.1280
10.1159/000071769
10.1097/00000658-200011000-00001
10.1097/00004836-200207000-00012
10.1097/00004836-200204000-00018
10.1002/bjs.1800620615
10.1046/j.0007-1323.2001.02025.x
10.1046/j.1365-2168.1998.00674.x
10.1007/978-3-642-83027-3_19
10.1111/j.1572-0241.2001.03966.x
10.1159/000055810
10.1046/j.1365-2168.2000.01298.x
10.1136/gut.37.1.121
10.1097/00006676-200204000-00002
10.1001/archsurg.135.9.1048
ContentType Journal Article
DBID AAYXX
CITATION
DOI 10.1590/S0100-69912006000300007
DatabaseName CrossRef
DatabaseTitle CrossRef
DatabaseTitleList CrossRef
DeliveryMethod fulltext_linktorsrc
EISSN 0100-6991
EndPage 168
ExternalDocumentID 10_1590_S0100_69912006000300007
GroupedDBID 123
29P
2WC
AAYXX
ABXHO
ADBBV
ALMA_UNASSIGNED_HOLDINGS
APOWU
AZFZN
BAWUL
BCNDV
CITATION
DIK
E3Z
F5P
GROUPED_DOAJ
IPNFZ
OK1
OVT
PGMZT
RIG
RNS
RPM
RSC
SCD
ID FETCH-LOGICAL-c1517-844173480d949338bf252813f655b1e1181834ae5bf2d109d11b8e06d11b82043
ISSN 0100-6991
IngestDate Tue Jul 01 04:39:22 EDT 2025
Thu Apr 24 22:54:22 EDT 2025
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 3
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c1517-844173480d949338bf252813f655b1e1181834ae5bf2d109d11b8e06d11b82043
OpenAccessLink https://www.scielo.br/j/rcbc/a/NPv7cXqv5hZTgQQdxQbFntK/?lang=pt&format=pdf
PageCount 8
ParticipantIDs crossref_primary_10_1590_S0100_69912006000300007
crossref_citationtrail_10_1590_S0100_69912006000300007
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2006-06-00
PublicationDateYYYYMMDD 2006-06-01
PublicationDate_xml – month: 06
  year: 2006
  text: 2006-06-00
PublicationDecade 2000
PublicationTitle Revista do Colégio Brasileiro de Cirurgiões
PublicationYear 2006
References Halonen KI (ref13) 2003; 3
Lankisch PG (ref25) 2001; 96
Bradley EL (ref1) 1994
Uhl W (ref12) 1998; 85
Büchler M (ref10) 1987
Lankisch PG (ref16) 2002; 24
Bittner R (ref17) 1987
Dervenis CG (ref5) 2001; 1
Büchler P (ref21) 1991; 28
Ranson JH (ref2) 1974; 61
Bank S (ref8) 2002; 35
Buchler MW (ref18) 2000; 232
Beger HG (ref20) 1991; 38
Meek K (ref15) 2000; 135
Beger HG (ref19) 1987
De Beaux AC (ref23) 1995; 37
Yadav D (ref24) 2002
Kylanpaa-Back (ref11) 2000; 87
Carmona-Sanchez R (ref14) 2000; 135
McKay CJ (ref4) 1999; 79
Smotkin J (ref7) 2002; 34
Buter A (ref22) 2002; 89
Imrie CW (ref3) 1975; 62
Blum T (ref6) 2001; 1
Triester SL (ref9) 2002; 34
Renteria JM (ref26) 1999
References_xml – volume: 1
  start-page: 237
  issue: 3
  year: 2001
  ident: ref6
  article-title: Fatal outcome in acute pancreatitis: its occurrence and early prediction
  publication-title: Pancreatology
  doi: 10.1159/000055817
– volume: 79
  start-page: 733
  issn: 0039-6109
  issue: 4
  year: 1999
  ident: ref4
  article-title: Staging of acute pancreatitis: Is it important?
  publication-title: Surg Clin North Am
  doi: 10.1016/S0039-6109(05)70039-6
– volume: 34
  start-page: 167
  issn: 0192-0790
  issue: 2
  year: 2002
  ident: ref9
  article-title: Prognostic factors in acute pancreatitis
  publication-title: J Clin Gastroenterol
  doi: 10.1097/00004836-200202000-00014
– volume: 135
  start-page: 1280
  issn: 0004-0010
  issue: 11
  year: 2000
  ident: ref14
  article-title: Potential harmful effect of iodinated intravenous contrast medium on the clinical course of mild acute pancreatitis
  publication-title: Arch Surg
  doi: 10.1001/archsurg.135.11.1280
– volume: 3
  start-page: 309
  issue: 4
  year: 2003
  ident: ref13
  article-title: Predicting fatal outcome in the early phase of severe acute pancreatitis by using novel prognostic models
  publication-title: Pancreatology
  doi: 10.1159/000071769
– volume: 232
  start-page: 619
  issn: 0003-4932
  issue: 5
  year: 2000
  ident: ref18
  article-title: Acute necrotizing pancreatitis: treatment strategy according to the status of infection
  publication-title: Ann Surg
  doi: 10.1097/00000658-200011000-00001
– volume: 38
  start-page: 92
  issn: 0172-6390
  issue: 2
  year: 1991
  ident: ref20
  article-title: Surgery in acute pancreatitis
  publication-title: Hepatogastroenterology
– volume: 35
  start-page: 50
  issn: 0192-0790
  issue: 1
  year: 2002
  ident: ref8
  article-title: Evaluation of factors that have reduced mortality from acute pancreatitis over the past 20 years
  publication-title: J Clin Gastroenterol
  doi: 10.1097/00004836-200207000-00012
– start-page: 27
  volume-title: The necessity for a clinical classification of acute pancreatitis the Atlanta system
  year: 1994
  ident: ref1
– volume: 34
  start-page: 459
  issn: 0192-0790
  issue: 4
  year: 2002
  ident: ref7
  article-title: Laboratory diagnostic tests in acute pancreatitis
  publication-title: J Clin Gastroenterol
  doi: 10.1097/00004836-200204000-00018
– volume: 62
  start-page: 490
  issn: 0007-1323
  issue: 6
  year: 1975
  ident: ref3
  article-title: A prospective study of acute pancreatitis
  publication-title: Br J Surg
  doi: 10.1002/bjs.1800620615
– issn: 0002-9270
  year: 2002
  ident: ref24
  article-title: A critical evaluation of laboratory tests in acute pancreatitis
  publication-title: Am J Gastroenterol
– year: 1999
  ident: ref26
– volume: 28
  start-page: 661
  issn: 0889-8553
  issue: 3
  year: 1991
  ident: ref21
  article-title: Surgical aproach in patients with acute pancreatitis: Is infected or sterile necrosis an indication? In whom, should this be done, when and why?
  publication-title: Gastroenterol Clin North Am
– volume: 89
  start-page: 298
  issn: 0007-1323
  issue: 3
  year: 2002
  ident: ref22
  article-title: Dynamic nature of early organ dysfunction determines outcome in acute pancreatitis
  publication-title: Br J Surg
  doi: 10.1046/j.0007-1323.2001.02025.x
– volume: 85
  start-page: 618
  issn: 0007-1323
  issue: 5
  year: 1998
  ident: ref12
  article-title: Experimental study of novel phospholipase A2 inhibitors in acute pancreatitis
  publication-title: Br J Surg
  doi: 10.1046/j.1365-2168.1998.00674.x
– volume: 61
  start-page: 443
  issn: 0002-9270
  issue: 6
  year: 1974
  ident: ref2
  article-title: Objective early identification of severe acute pancreatitis
  publication-title: Am J Gastroenterol
– start-page: 143
  volume-title: Biochemical staging of acute pancreatitis
  year: 1987
  ident: ref10
  doi: 10.1007/978-3-642-83027-3_19
– start-page: 216
  volume-title: Pancreatic abscess and injected pancreatic necrosis: different local septic complications in acute pancreatitis
  year: 1987
  ident: ref17
– volume: 96
  start-page: 2081
  issn: 0002-9270
  issue: 7
  year: 2001
  ident: ref25
  article-title: Hemoconcentration: an early marker of severe and or necrotizing pancreatitis? A critical appraisal
  publication-title: Am J Gastroenterol
  doi: 10.1111/j.1572-0241.2001.03966.x
– volume: 1
  start-page: 201
  issue: 3
  year: 2001
  ident: ref5
  article-title: Staging acute pancreatitis: where are we now?
  publication-title: Pancreatology
  doi: 10.1159/000055810
– volume: 87
  start-page: 49
  issn: 0007-1323
  issue: 1
  year: 2000
  ident: ref11
  article-title: Reliable screening for acute pancreatitis with rapid urine trypsinogen-2 test strip
  publication-title: Br J Surg
  doi: 10.1046/j.1365-2168.2000.01298.x
– volume: 37
  start-page: 121
  issn: 0017-5749
  issue: 1
  year: 1995
  ident: ref23
  article-title: Factors influencing morbidity and mortality in acute Pancreatitis: an analysis of 279 cases
  publication-title: Gut
  doi: 10.1136/gut.37.1.121
– volume: 24
  start-page: 217
  issn: 0885-3177
  issue: 3
  year: 2002
  ident: ref16
  article-title: The APACHE II score is unreliable to diagnose necrotizing pancreatitis on admission to hospital
  publication-title: Pancreas
  doi: 10.1097/00006676-200204000-00002
– volume: 135
  start-page: 1048
  issn: 0004-0010
  issue: 9
  year: 2000
  ident: ref15
  article-title: Simplified admission criterion for predicting severe complications of gallstone pancreatitis
  publication-title: Arch Surg
  doi: 10.1001/archsurg.135.9.1048
– start-page: 198
  volume-title: Prognostic criteria in necrotizing pancreatitis
  year: 1987
  ident: ref19
SSID ssj0043193
Score 1.6282883
Snippet OBJETIVO: Correlacionar a avaliação clínico-laboratorial inicial simplificada com a gravidade da pancreatite aguda e a presença de necrose. MÉTODO: Foi...
SourceID crossref
SourceType Enrichment Source
Index Database
StartPage 161
Title O papel da avaliação inicial simplificada no prognóstico da pancreatite aguda
Volume 33
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3NbtQwELaWcuGCQIAoP5UP3KKUeBMnzhFWrSpQKaBW6m3lxM4qUhVX2YQDr8OBB-AR9qm4MWM72agtKuWSXXkzE2vniz3_JuSNYrECrQLAq7IqTMqSh1InMkx0zgW8Tyqx3faPP6VHZ8mHc34-m_2eZC31XbFffr-xruR_pApjIFeskr2DZEemMADfQb5wBQnD9Z9kfBJcYvpSoGQgv6HDwoa9M3uNTYA1j7YepMa08QqLR2TQGJuT1eBN72Ps0myQHhYFpz92OpCr3tvpQ-duLEHvZKAMOhpcbH1VGwCGXMOqUrfAQgeLuu3bVW0Z821q4kK2Dd5iXa-WlrUlEC9wylawW694szY-LOEegvknAGETHOq2BSbjHnLQu2mwi_oKxTG8uf06-CrXZgwmYd_R1mcF9xidqle9LxWYODyGxKzBBxqBxZu7Q7729Q1jfmF3HTY8gOPJKs1SNtnwmTvX59pewvPIRrMH1jgXa0KiXrXdPoeUgSu76pjriFYWsFpaRstrjO6R-3OwcPDUkY9fxgAYqHWuX_TwcJ-aCIze_mVGE8VqoiGdPiIPvWlD3zmcPiYz3Twhn0-oxShVkjqMbn5ufhjqsUmn2KSNoRabm18Wl0gzwSW1uHxKzg4PThdHoT_FIyxBmwQVCA-5ixMRqTzJ41gU1ZzPBYurlPOCaSx8FnEiNYcfFItyxVghdJTaT6zcfkZ2GtPo54SmosjSrBIpz1hSikKmKskkLDBZmZdSi12SDn_BsvQt7vGklYvlLULYJdFIeOm6vNxG8uLuJC_Jgy2eX5Gdru31a1Bpu2LPuoL2LAT-AO6bktA
linkProvider Colorado Alliance of Research Libraries
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=O+papel+da+avalia%C3%A7%C3%A3o+inicial+simplificada+no+progn%C3%B3stico+da+pancreatite+aguda&rft.jtitle=Revista+do+Col%C3%A9gio+Brasileiro+de+Cirurgi%C3%B5es&rft.au=Carneiro%2C+M%C3%A1rcio+Cavalcante&rft.au=Manso%2C+Jos%C3%A9+Eduardo+Ferreira&rft.au=Eul%C3%A1lio%2C+Jos%C3%A9+Marcus+Raso&rft.au=Renteria%2C+Juan+Miguel&rft.date=2006-06-01&rft.issn=0100-6991&rft.eissn=0100-6991&rft.volume=33&rft.issue=3&rft.spage=161&rft.epage=168&rft_id=info:doi/10.1590%2FS0100-69912006000300007&rft.externalDBID=n%2Fa&rft.externalDocID=10_1590_S0100_69912006000300007
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0100-6991&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0100-6991&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0100-6991&client=summon