CD79a Is Associated with Central Nervous System Infiltration of Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

• Published in: Blood Vol. 132; no. Supplement 1; p. 386
• Main Authors: Lenk, Lennart, Vogiatzi, Fotini, Carlet, Michela, Vokuhl, Christian, Cario, Gunnar, Schrappe, Martin, Jeremias, Irmela, Fuhrmann, Stephan, Hobeika, Elias, Jumaa, Hassan, Alsadeq, Ameera, Schewe, Denis Martin
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 29.11.2018

▪ Despite the advances in the treatment of pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL), infiltration of the central nervous system (CNS) remains a clinical challenge. Certain cytogenetic subtypes such as E2A-PBX1-and BCR-ABL-positive BCP-ALL confer a higher risk for CNS involve...