4-aminosalicylic acid as a coupling reagent for spectrophotometric determination of mesalazine in an aqueous medium

• Published in: Tikrit Journal of Pure Science Vol. 29; no. 3; pp. 18 - 27
• Main Authors: Mohamed Y. Dhamra, Esraa A.Ahmad
• Format: Journal Article
• Language: English
• Published: Tikrit University 25.06.2024
• Subjects: 4-aminosalicylic acid; determination; mesalazine; oxidative coupling; spectrophotometric

A sensitive, rapid, and inexpensive spectrophotometric method for the determination of mesalazine in an alkaline medium by an oxidative coupling reaction was developed. At a wavelength of about 600 nm,  mesalazine could be estimated in the range (0.1–14) µg/ml with high sensitivity, since the molar...