SEROPREVALENCE OF HSV, HBsAg & HCV IN STD CLINIC ATTENDEES OF A TERTIARY CARE STATE HEADQUARTERS HOSPITAL
BACKGROUND Sexual activity in humans is meant for both procreative and recreational purposes. However, with the discovery of HIV/AIDS in 1981, concerns developed worldwide over unprotected sex. The unprotected sexual activity is contributing for transmission of symptomatic and asymptomatic STIs such...
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Published in | Journal of evolution of medical and dental sciences Vol. 6; no. 63; pp. 4609 - 4614 |
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Language | English |
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Akshantala Enterprises Private Limited
07.08.2017
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Abstract | BACKGROUND Sexual activity in humans is meant for both procreative and recreational purposes. However, with the discovery of HIV/AIDS in 1981, concerns developed worldwide over unprotected sex. The unprotected sexual activity is contributing for transmission of symptomatic and asymptomatic STIs such as HIV, HBsAg and HCV. The aim is to study seroprevalence of HBsAg, HSV & anti-HCV antibodies in STD clinic attendees of Osmania Medical College/Osmania General Hospital, Hyderabad. MATERIALS AND METHODS It is a descriptive study (observational study) conducted from January 2015-December 2015 at STD Clinic OPD. A total of 3,583 patients who attended the STD Clinic during the above period were studied and patients having direct or indirect risk factors were serotested for the 3 viral infections after inclusion and exclusion criteria with informed consent. A 5 mL of venous blood is collected and the separated serum is tested for HSV 1&2, HBsAg and Anti-HCV antibodies by using ELISA kits. It is ensured that the test kits used have >95% sensitivity and specificity. Settings & Design-All eligible patients attending STD Clinic, Dept. of DVL, Osmania Medical College/Osmania General Hospital, Hyderabad were included in the study after inclusion and exclusion criteria with informed consent. A consecutive sampling methodology with zero intervals is followed. A percentage analysis method is used to derive the conclusions. RESULTS A total of 473 cases are found to be seropositives out of the 3,583 STD clinic attendees for either of 3 STIs showing a seroprevalence of 13.20%, in which male seroprevalence is 13.56% (258 cases) and female seroprevalence is 12.80% (215 cases). In the studied population of 3583,412 cases were seropositives for HSV Antibodies with seroprevalence of 11.5%, 39 were HBsAg Antibodies positive with seroprevalence of 1.09% and 22 cases were positive for HCV antibodies with seroprevalence of 0.61%. The seropositivity in males and females respectively for HSV is 11.56% and 11.43%; for HBsAg is 1.26% and 0.89%; for HCV is 0.74% and 0.48%. The illiterates (376 of 473=79.49%) and people of low socioeconomic status (371 of 473=78%) are more affected. While 234 of 258 men are having either Premarital, Extramarital or combination accounting to 90.70%, 176 of 215 (81.86%) women are confined to marital sex. CONCLUSION The awareness on STIs needs to be well informed before the start of the sexual activity by incorporating the STI/RTI education in school and college curriculum, through IEC activities like mass media campaigns, print & electronic media, by using local cultural festivals, gatherings and through marriage institutions. The at-risk populations such as Sex workers, MSM & IDUs should be covered through specific targeted interventions by utilising NGOs, local bodies and associations. KEYWORDS Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2, Hepatitis B Virus, HSV 1, HSV 2, Anti-HCV Antibodies, Sexually Transmitted Viral Infections, STD Clinic, STD Clinic Attendees. |
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AbstractList | BACKGROUND Sexual activity in humans is meant for both procreative and recreational purposes. However, with the discovery of HIV/AIDS in 1981, concerns developed worldwide over unprotected sex. The unprotected sexual activity is contributing for transmission of symptomatic and asymptomatic STIs such as HIV, HBsAg and HCV. The aim is to study seroprevalence of HBsAg, HSV & anti-HCV antibodies in STD clinic attendees of Osmania Medical College/Osmania General Hospital, Hyderabad. MATERIALS AND METHODS It is a descriptive study (observational study) conducted from January 2015-December 2015 at STD Clinic OPD. A total of 3,583 patients who attended the STD Clinic during the above period were studied and patients having direct or indirect risk factors were serotested for the 3 viral infections after inclusion and exclusion criteria with informed consent. A 5 mL of venous blood is collected and the separated serum is tested for HSV 1&2, HBsAg and Anti-HCV antibodies by using ELISA kits. It is ensured that the test kits used have >95% sensitivity and specificity. Settings & Design-All eligible patients attending STD Clinic, Dept. of DVL, Osmania Medical College/Osmania General Hospital, Hyderabad were included in the study after inclusion and exclusion criteria with informed consent. A consecutive sampling methodology with zero intervals is followed. A percentage analysis method is used to derive the conclusions. RESULTS A total of 473 cases are found to be seropositives out of the 3,583 STD clinic attendees for either of 3 STIs showing a seroprevalence of 13.20%, in which male seroprevalence is 13.56% (258 cases) and female seroprevalence is 12.80% (215 cases). In the studied population of 3583,412 cases were seropositives for HSV Antibodies with seroprevalence of 11.5%, 39 were HBsAg Antibodies positive with seroprevalence of 1.09% and 22 cases were positive for HCV antibodies with seroprevalence of 0.61%. The seropositivity in males and females respectively for HSV is 11.56% and 11.43%; for HBsAg is 1.26% and 0.89%; for HCV is 0.74% and 0.48%. The illiterates (376 of 473=79.49%) and people of low socioeconomic status (371 of 473=78%) are more affected. While 234 of 258 men are having either Premarital, Extramarital or combination accounting to 90.70%, 176 of 215 (81.86%) women are confined to marital sex. CONCLUSION The awareness on STIs needs to be well informed before the start of the sexual activity by incorporating the STI/RTI education in school and college curriculum, through IEC activities like mass media campaigns, print & electronic media, by using local cultural festivals, gatherings and through marriage institutions. The at-risk populations such as Sex workers, MSM & IDUs should be covered through specific targeted interventions by utilising NGOs, local bodies and associations. KEYWORDS Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2, Hepatitis B Virus, HSV 1, HSV 2, Anti-HCV Antibodies, Sexually Transmitted Viral Infections, STD Clinic, STD Clinic Attendees. Sexual activity in humans is meant for both procreative and recreational purposes. However, with the discovery of HIV/AIDS in 1981, concerns developed worldwide over unprotected sex. The unprotected sexual activity is contributing for transmission of symptomatic and asymptomatic STIs such as HIV, HBsAg and HCV. It is a descriptive study (observational study) conducted from January 2015-December 2015 at STD Clinic OPD. A total of 3,583 patients who attended the STD Clinic during the above period were studied and patients having direct or indirect risk factors were serotested for the 3 viral infections after inclusion and exclusion criteria with informed consent. A 5 mL of venous blood is collected and the separated serum is tested for HSV 1&2, HBsAg and Anti-HCV antibodies by using ELISA kits. It is ensured that the test kits used have >95% sensitivity and specificity. A total of 473 cases are found to be seropositives out of the 3,583 STD clinic attendees for either of 3 STIs showing a seroprevalence of 13.20%, in which male seroprevalence is 13.56% (258 cases) and female seroprevalence is 12.80% (215 cases). In the studied population of 3583,412 cases were seropositives for HSV Antibodies with seroprevalence of 11.5%, 39 were HBsAg Antibodies positive with seroprevalence of 1.09% and 22 cases were positive for HCV antibodies with seroprevalence of 0.61%. The seropositivity in males and females respectively for HSV is 11.56% and 11.43%; for HBsAg is 1.26% and 0.89%; for HCV is 0.74% and 0.48%. The illiterates (376 of 473=79.49%) and people of low socioeconomic status (371 of 473=78%) are more affected. While 234 of 258 men are having either Premarital, Extramarital or combination accounting to 90.70%, 176 of 215 (81.86%) women are confined to marital sex. The awareness on STIs needs to be well informed before the start of the sexual activity by incorporating the STI/RTI education in school and college curriculum, through IEC activities like mass media campaigns, print & electronic media, by using local cultural festivals, gatherings and through marriage institutions. The at-risk populations such as Sex workers, MSM & IDUs should be covered through specific targeted interventions by utilising NGOs, local bodies and associations. |
Audience | Academic |
Author | Godha, Venkata Ramana Ananthula, Venkata Krishna Prasad, J. V. D. S Dudhipala, Subhash Reddy Kiran, Raghu Kuman, Veena Pinjala, Padmaja Prasad, K.N |
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Cites_doi | 10.1016/j.jhep.2014.07.027 10.5812/hepatmon.13313 10.1146/annurev.iy.13.040195.000333 10.1086/491742 10.1086/343739 10.1155/2014/516859 10.4103/0255-0857.38855 10.1111/j.1469-0691.1999.tb00706.x 10.1097/00007435-200005000-00011 10.1590/S0074-02762001000500007 10.1016/j.immuni.2013.12.010 10.1093/ije/27.1.127 10.26719/2013.19.7.589 10.1155/2012/689726 10.1186/1743-422X-8-225 10.4103/0019-5359.32092 10.5455/2320-6012.ijrms20150154 |
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References | FV (ref2) 1995; 13 Gacche (ref13) 2012; 2012 ref14 ref0 ref17 Nowicki (ref4) 2005; 192 ref16 Khan (ref10) 2014; 2014 Chawla (ref11) 2008; 26 ref8 Gholamreza (ref15) 2007; 61 ref7 SH (ref1) 2014; 40 Rotily (ref20) 1999; 5 ref9 ref3 Khan (ref12) 2011; 8 ref5 Oliveira (ref19) 2001; 96 Cusini (ref6) 2000; 27 De Laar (ref18) 1998; 27 |
References_xml | – ident: ref17 doi: 10.1016/j.jhep.2014.07.027 – ident: ref16 doi: 10.5812/hepatmon.13313 – volume: 13 start-page: 29 year: 1995 ident: ref2 article-title: Hepatitis B virus immunopathogenesis publication-title: Annu Rev Immunol doi: 10.1146/annurev.iy.13.040195.000333 contributor: fullname: FV – ident: ref3 – volume: 192 start-page: 1557 issue: 9 year: 2005 ident: ref4 article-title: Presence of hepatitis C virus (HCV) RNA in the genital tracts of HCV/HIV-1-coinfected women publication-title: J Infect Dis doi: 10.1086/491742 contributor: fullname: Nowicki – ident: ref5 doi: 10.1086/343739 – volume: 2014 start-page: 4 year: 2014 ident: ref10 article-title: Seropositivity and coinfection of hepatitis B and C among patients seeking hospital care in Islamabad, Pakistan publication-title: BioMed Research International doi: 10.1155/2014/516859 contributor: fullname: Khan – volume: 26 start-page: 34 issue: 1 year: 2008 ident: ref11 article-title: Community-based study on seroprevalence of herpes simplex virus type 2 infection in New Delhi publication-title: Indian J Med Microbiol doi: 10.4103/0255-0857.38855 contributor: fullname: Chawla – volume: 5 start-page: 733 issue: 12 year: 1999 ident: ref20 article-title: Prevalence of HCV and HIV antibodies and related risk factors among entrants to the main southeastern French prison publication-title: Clinical Microbiology and Infection doi: 10.1111/j.1469-0691.1999.tb00706.x contributor: fullname: Rotily – volume: 27 start-page: 292 issue: 5 year: 2000 ident: ref6 article-title: Italian herpes forum publication-title: Sex Transm Dis doi: 10.1097/00007435-200005000-00011 contributor: fullname: Cusini – volume: 96 start-page: 635 issue: 5 year: 2001 ident: ref19 article-title: Hepatitis B infection among patients attending a sexually transmitted diseases clinic in Rio de Janeiro, Brazil publication-title: Mem Inst Oswaldo Cruz doi: 10.1590/S0074-02762001000500007 contributor: fullname: Oliveira – volume: 40 start-page: 13 issue: 1 year: 2014 ident: ref1 article-title: Immune responses to HCV and other hepatitis viruses publication-title: Immunity doi: 10.1016/j.immuni.2013.12.010 contributor: fullname: SH – volume: 27 start-page: 127 issue: 1 year: 1998 ident: ref18 article-title: Prevalence and correlates of herpes simplex virus type 2 infection: evaluation of behavioural risk factors publication-title: Int J Epidemiol doi: 10.1093/ije/27.1.127 contributor: fullname: De Laar – ident: ref14 doi: 10.26719/2013.19.7.589 – volume: 2012 start-page: 4 year: 2012 ident: ref13 article-title: Seroprevalence and risk factors for hepatitis c virus infection among general population in central region of Yemen publication-title: Hepatitis Research and Treatment doi: 10.1155/2012/689726 contributor: fullname: Gacche – ident: ref9 – volume: 8 start-page: 225 year: 2011 ident: ref12 article-title: Hepatitis B virus infection among different sex and age groups in Pakistani Punjab publication-title: Virology Journal doi: 10.1186/1743-422X-8-225 contributor: fullname: Khan – ident: ref8 – ident: ref0 – volume: 61 start-page: 263 issue: 5 year: 2007 ident: ref15 article-title: Seroprevalence of hepatitis B virus and its co-infection with hepatitis D virus and hepatitis C virus in Iranian adult population publication-title: Indian J Med Sci doi: 10.4103/0019-5359.32092 contributor: fullname: Gholamreza – ident: ref7 doi: 10.5455/2320-6012.ijrms20150154 |
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Snippet | BACKGROUND Sexual activity in humans is meant for both procreative and recreational purposes. However, with the discovery of HIV/AIDS in 1981, concerns... Sexual activity in humans is meant for both procreative and recreational purposes. However, with the discovery of HIV/AIDS in 1981, concerns developed... |
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Title | SEROPREVALENCE OF HSV, HBsAg & HCV IN STD CLINIC ATTENDEES OF A TERTIARY CARE STATE HEADQUARTERS HOSPITAL |
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