Vcam1+ Fibro-adipogenic Progenitors Mark Fatty Infiltration in Chronic Limb Threatening Ischemia

Saved in:
Bibliographic Details
Published inJVS-vascular science p. 100295
Main Authors Dai, Qunsheng, Wan, Changxin, Xu, Yueyuan, Fei, Kaileen, Olivere, Lindsey A., Shafique, Hana, Sadeghmousavi, Shaghayegh, Johnson, Camryn, Garrett, Brianna, Akers, Leo, Peters, Derek, Otto, James, Kontos, Christopher D., Ji, Zhiceng, Diao, Yarui, Southerland, Kevin W.
Format Journal Article
LanguageEnglish
Published 01.08.2025
Online AccessGet full text

Cover

ArticleNumber 100295
Author Kontos, Christopher D.
Ji, Zhiceng
Peters, Derek
Wan, Changxin
Diao, Yarui
Shafique, Hana
Sadeghmousavi, Shaghayegh
Garrett, Brianna
Johnson, Camryn
Akers, Leo
Xu, Yueyuan
Dai, Qunsheng
Olivere, Lindsey A.
Otto, James
Southerland, Kevin W.
Fei, Kaileen
Author_xml – sequence: 1
  givenname: Qunsheng
  surname: Dai
  fullname: Dai, Qunsheng
– sequence: 2
  givenname: Changxin
  surname: Wan
  fullname: Wan, Changxin
– sequence: 3
  givenname: Yueyuan
  surname: Xu
  fullname: Xu, Yueyuan
– sequence: 4
  givenname: Kaileen
  surname: Fei
  fullname: Fei, Kaileen
– sequence: 5
  givenname: Lindsey A.
  surname: Olivere
  fullname: Olivere, Lindsey A.
– sequence: 6
  givenname: Hana
  orcidid: 0000-0002-0158-893X
  surname: Shafique
  fullname: Shafique, Hana
– sequence: 7
  givenname: Shaghayegh
  surname: Sadeghmousavi
  fullname: Sadeghmousavi, Shaghayegh
– sequence: 8
  givenname: Camryn
  surname: Johnson
  fullname: Johnson, Camryn
– sequence: 9
  givenname: Brianna
  surname: Garrett
  fullname: Garrett, Brianna
– sequence: 10
  givenname: Leo
  surname: Akers
  fullname: Akers, Leo
– sequence: 11
  givenname: Derek
  surname: Peters
  fullname: Peters, Derek
– sequence: 12
  givenname: James
  surname: Otto
  fullname: Otto, James
– sequence: 13
  givenname: Christopher D.
  surname: Kontos
  fullname: Kontos, Christopher D.
– sequence: 14
  givenname: Zhiceng
  surname: Ji
  fullname: Ji, Zhiceng
– sequence: 15
  givenname: Yarui
  surname: Diao
  fullname: Diao, Yarui
– sequence: 16
  givenname: Kevin W.
  surname: Southerland
  fullname: Southerland, Kevin W.
BookMark eNpNkE1PAjEYhBuDiYj8Aw-9m8V-LxwNEd0Eowf0Wt_tttCVbUm7MeHfy4oHTzOZzMzhuUajEINF6JaSGSVU3bez9jtn42eMMHmKCFvICzRmSqmCS8JH__wVmubcklNHUs7mcow-Pwx09A6vfJ1iAY0_xK0N3uC39Gv6mDJ-gfSFV9D3R1wF5_d9gt7HgH3Ay12KQ33tuxpvdslCf1qFLa6y2dnOww26dLDPdvqnE_S-etwsn4v161O1fFgXhgolC-Mc4Q0VZWldbdSCOmHnwtUggFoFC1JKoJJJIOUcamUJNEIQ5kTdOC6c4RMkzr8mxZyTdfqQfAfpqCnRAyjd6jMoPYDSZ1D8Bxy6YQk
Cites_doi 10.1186/s13073-023-01250-y
10.1161/CIRCRESAHA.123.323161
10.1016/j.stemcr.2023.03.001
10.1016/j.avsg.2022.07.009
10.1096/fj.14-254011
10.1038/s41418-020-0551-y
10.3390/jcm10173963
10.1016/j.jacbts.2022.12.006
10.1038/ncb2014
10.1016/j.stem.2021.04.008
10.1161/JAHA.118.015929
10.1210/en.2004-1050
10.1038/s41598-024-63626-3
10.2147/VHRM.S209241
10.1038/s41514-024-00147-3
10.1253/circj.CJ-18-0726
10.1016/S0140-6736(13)61249-0
10.1016/j.cmet.2021.10.001
10.1038/s41598-019-39538-y
10.1038/s41467-022-34191-y
10.1155/2012/172957
10.1038/s41467-018-06068-6
10.1161/ATVBAHA.120.313831
10.1038/s41536-023-00291-6
10.1038/nm.3869
10.1016/j.jvs.2019.02.016
10.1172/jci.insight.123235
10.1016/j.celrep.2020.107597
10.1186/s13395-020-00236-3
10.1016/j.celrep.2019.04.074
10.1016/j.jvs.2015.06.139
10.1042/CS20150435
10.1038/s42003-023-04504-y
10.3390/jcm10030548
10.1056/NEJMoa2207899
10.1161/CIRCULATIONAHA.107.736447
10.1038/s41419-024-06851-y
10.3390/jcm9123974
10.1016/j.jvs.2020.03.050
10.1038/ncb2015
10.1152/ajpregu.00525.2012
ContentType Journal Article
DBID AAYXX
CITATION
DOI 10.1016/j.jvssci.2025.100295
DatabaseName CrossRef
DatabaseTitle CrossRef
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 2666-3503
ExternalDocumentID 10_1016_j_jvssci_2025_100295
GroupedDBID .1-
.FO
1P~
AAEDW
AALRI
AAXUO
AAYWO
AAYXX
ACVFH
ADCNI
ADVLN
AEUPX
AFJKZ
AFPUW
AFRHN
AIGII
AITUG
AJUYK
AKBMS
AKYEP
ALMA_UNASSIGNED_HOLDINGS
AMRAJ
APXCP
CITATION
EBS
FDB
GROUPED_DOAJ
M41
M~E
OK1
ROL
RPM
Z5R
ID FETCH-LOGICAL-c1465-cff03d1477efbc691f4e84fba4a1e6a9075a1525a078ab6e0ad4402f4bdf34fc3
ISSN 2666-3503
IngestDate Wed Aug 27 16:30:25 EDT 2025
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c1465-cff03d1477efbc691f4e84fba4a1e6a9075a1525a078ab6e0ad4402f4bdf34fc3
ORCID 0000-0002-0158-893X
OpenAccessLink https://dx.doi.org/10.1016/j.jvssci.2025.100295
ParticipantIDs crossref_primary_10_1016_j_jvssci_2025_100295
PublicationCentury 2000
PublicationDate 2025-8-00
PublicationDateYYYYMMDD 2025-08-01
PublicationDate_xml – month: 08
  year: 2025
  text: 2025-8-00
PublicationDecade 2020
PublicationTitle JVS-vascular science
PublicationYear 2025
References Uezumi (10.1016/j.jvssci.2025.100295_bib18) 2010; 12
Fowkes (10.1016/j.jvssci.2025.100295_bib1) 2013; 382
Wosczyna (10.1016/j.jvssci.2025.100295_bib22) 2021; 28
Southerland (10.1016/j.jvssci.2025.100295_bib25) 2023; 15
Malecova (10.1016/j.jvssci.2025.100295_bib30) 2018; 9
Wilburn (10.1016/j.jvssci.2025.100295_bib6) 2024; 14
Nawaz (10.1016/j.jvssci.2025.100295_bib40) 2022; 13
Cluff (10.1016/j.jvssci.2025.100295_bib11) 2013; 305
Krishna (10.1016/j.jvssci.2025.100295_bib41) 2016; 130
Ferreira (10.1016/j.jvssci.2025.100295_bib13) 2023; 88
Wosczyna (10.1016/j.jvssci.2025.100295_bib19) 2019; 27
Duff (10.1016/j.jvssci.2025.100295_bib4) 2019; 15
Cong (10.1016/j.jvssci.2025.100295_bib9) 2020; 9
Camps (10.1016/j.jvssci.2025.100295_bib23) 2020; 31
McClung (10.1016/j.jvssci.2025.100295_bib28) 2016; 64
Kosmac (10.1016/j.jvssci.2025.100295_bib7) 2020; 9
Ryan (10.1016/j.jvssci.2025.100295_bib10) 2018; 3
De Micheli (10.1016/j.jvssci.2025.100295_bib37) 2020; 10
Fitzgerald (10.1016/j.jvssci.2025.100295_bib24) 2023; 6
Reggio (10.1016/j.jvssci.2025.100295_bib34) 2019; 9
Lemos (10.1016/j.jvssci.2025.100295_bib21) 2015; 21
Dong (10.1016/j.jvssci.2025.100295_bib35) 2014; 28
Reggio (10.1016/j.jvssci.2025.100295_bib31) 2020; 27
McDermott (10.1016/j.jvssci.2025.100295_bib8) 2020; 40
Farup (10.1016/j.jvssci.2025.100295_bib39) 2021; 33
Ma (10.1016/j.jvssci.2025.100295_bib15) 2021; 10
Sugai (10.1016/j.jvssci.2025.100295_bib12) 2018; 82
Zhang (10.1016/j.jvssci.2025.100295_bib42) 2024; 15
Dong (10.1016/j.jvssci.2025.100295_bib29) 2023; 8
Dokun (10.1016/j.jvssci.2025.100295_bib27) 2008; 117
Joe (10.1016/j.jvssci.2025.100295_bib17) 2010; 12
Tuttle (10.1016/j.jvssci.2025.100295_bib14) 2012; 2012
Wang (10.1016/j.jvssci.2025.100295_bib36) 2005; 146
Pass (10.1016/j.jvssci.2025.100295_bib43) 2023; 133
Fu (10.1016/j.jvssci.2025.100295_bib32) 2023; 18
Padgett (10.1016/j.jvssci.2025.100295_bib26) 2016; 112
Pass (10.1016/j.jvssci.2025.100295_bib38) 2023; 133
Khattri (10.1016/j.jvssci.2025.100295_bib33) 2021; 10
Kotsaris (10.1016/j.jvssci.2025.100295_bib20) 2023; 8
Farber (10.1016/j.jvssci.2025.100295_bib3) 2022; 387
Vedder (10.1016/j.jvssci.2025.100295_bib16) 2020; 72
Conte (10.1016/j.jvssci.2025.100295_bib2) 2019; 69
Koutakis (10.1016/j.jvssci.2025.100295_bib5) 2024; 10
References_xml – volume: 15
  start-page: 95
  issue: 1
  year: 2023
  ident: 10.1016/j.jvssci.2025.100295_bib25
  article-title: Skeletal muscle regeneration failure in ischemic-damaged limbs is associated with pro-inflammatory macrophages and premature differentiation of satellite cells
  publication-title: Genome Med
  doi: 10.1186/s13073-023-01250-y
– volume: 133
  start-page: 791
  issue: 10
  year: 2023
  ident: 10.1016/j.jvssci.2025.100295_bib38
  article-title: Single-Nuclei RNA-Sequencing of the Gastrocnemius Muscle in Peripheral Artery Disease
  publication-title: Circ Res
  doi: 10.1161/CIRCRESAHA.123.323161
– volume: 112
  year: 2016
  ident: 10.1016/j.jvssci.2025.100295_bib26
  article-title: Methods for Acute and Subacute Murine Hindlimb Ischemia
  publication-title: J Vis Exp
– volume: 18
  start-page: 999
  issue: 4
  year: 2023
  ident: 10.1016/j.jvssci.2025.100295_bib32
  article-title: WNT7A suppresses adipogenesis of skeletal muscle mesenchymal stem cells and fatty infiltration through the alternative Wnt-Rho-YAP/TAZ signaling axis
  publication-title: Stem Cell Reports
  doi: 10.1016/j.stemcr.2023.03.001
– volume: 88
  start-page: 164
  year: 2023
  ident: 10.1016/j.jvssci.2025.100295_bib13
  article-title: Inflammation and Loss of Skeletal Muscle Mass in Chronic Limb Threatening Ischemia
  publication-title: Ann Vasc Surg
  doi: 10.1016/j.avsg.2022.07.009
– volume: 28
  start-page: 4123
  issue: 9
  year: 2014
  ident: 10.1016/j.jvssci.2025.100295_bib35
  article-title: Glucocorticoids increase adipocytes in muscle by affecting IL-4 regulated FAP activity
  publication-title: Faseb j
  doi: 10.1096/fj.14-254011
– volume: 27
  start-page: 2921
  issue: 10
  year: 2020
  ident: 10.1016/j.jvssci.2025.100295_bib31
  article-title: Adipogenesis of skeletal muscle fibro/adipogenic progenitors is affected by the WNT5a/GSK3/β-catenin axis
  publication-title: Cell Death Differ
  doi: 10.1038/s41418-020-0551-y
– volume: 10
  issue: 17
  year: 2021
  ident: 10.1016/j.jvssci.2025.100295_bib15
  article-title: The Impact of Lower Extremity Skeletal Muscle Atrophy and Myosteatosis on Revascularization Outcomes in Patients with Peripheral Arterial Disease
  publication-title: J Clin Med
  doi: 10.3390/jcm10173963
– volume: 8
  start-page: 702
  issue: 6
  year: 2023
  ident: 10.1016/j.jvssci.2025.100295_bib29
  article-title: IGF-1 Therapy Improves Muscle Size and Function in Experimental Peripheral Arterial Disease
  publication-title: JACC Basic Transl Sci
  doi: 10.1016/j.jacbts.2022.12.006
– volume: 12
  start-page: 143
  issue: 2
  year: 2010
  ident: 10.1016/j.jvssci.2025.100295_bib18
  article-title: Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle
  publication-title: Nat Cell Biol
  doi: 10.1038/ncb2014
– volume: 28
  start-page: 1323
  issue: 7
  year: 2021
  ident: 10.1016/j.jvssci.2025.100295_bib22
  article-title: Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells
  publication-title: Cell Stem Cell
  doi: 10.1016/j.stem.2021.04.008
– volume: 9
  issue: 10
  year: 2020
  ident: 10.1016/j.jvssci.2025.100295_bib7
  article-title: Correlations of Calf Muscle Macrophage Content With Muscle Properties and Walking Performance in Peripheral Artery Disease
  publication-title: J Am Heart Assoc
  doi: 10.1161/JAHA.118.015929
– volume: 146
  start-page: 2415
  issue: 5
  year: 2005
  ident: 10.1016/j.jvssci.2025.100295_bib36
  article-title: Secreted frizzled-related protein 1 modulates glucocorticoid attenuation of osteogenic activities and bone mass
  publication-title: Endocrinology
  doi: 10.1210/en.2004-1050
– volume: 14
  issue: 1
  year: 2024
  ident: 10.1016/j.jvssci.2025.100295_bib6
  article-title: Skeletal muscle desmin alterations following revascularization in peripheral artery disease claudicants
  publication-title: Sci Rep
  doi: 10.1038/s41598-024-63626-3
– volume: 15
  start-page: 187
  year: 2019
  ident: 10.1016/j.jvssci.2025.100295_bib4
  article-title: The burden of critical limb ischemia: a review of recent literature
  publication-title: Vasc Health Risk Manag
  doi: 10.2147/VHRM.S209241
– volume: 10
  start-page: 21
  issue: 1
  year: 2024
  ident: 10.1016/j.jvssci.2025.100295_bib5
  article-title: Oxidative damage in the gastrocnemius predicts long-term survival in patients with peripheral artery disease
  publication-title: NPJ Aging
  doi: 10.1038/s41514-024-00147-3
– volume: 82
  start-page: 3069
  issue: 12
  year: 2018
  ident: 10.1016/j.jvssci.2025.100295_bib12
  article-title: Decreased Psoas Muscle Computed Tomography Value Predicts Poor Outcome in Peripheral Artery Disease
  publication-title: Circ J
  doi: 10.1253/circj.CJ-18-0726
– volume: 382
  start-page: 1329
  issue: 9901
  year: 2013
  ident: 10.1016/j.jvssci.2025.100295_bib1
  article-title: Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis
  publication-title: Lancet
  doi: 10.1016/S0140-6736(13)61249-0
– volume: 33
  start-page: 2201
  issue: 11
  year: 2021
  ident: 10.1016/j.jvssci.2025.100295_bib39
  article-title: Human skeletal muscle CD90(+) fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients
  publication-title: Cell Metab
  doi: 10.1016/j.cmet.2021.10.001
– volume: 133
  start-page: 791
  issue: 10
  year: 2023
  ident: 10.1016/j.jvssci.2025.100295_bib43
  article-title: Single-nuclei RNA-sequencing of the gastrocnemius muscle in peripheral artery disease
  publication-title: Circ Res
  doi: 10.1161/CIRCRESAHA.123.323161
– volume: 9
  start-page: 4360
  issue: 1
  year: 2019
  ident: 10.1016/j.jvssci.2025.100295_bib34
  article-title: The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitors from dystrophic mice by affecting AKT signaling
  publication-title: Sci Rep
  doi: 10.1038/s41598-019-39538-y
– volume: 13
  start-page: 7058
  issue: 1
  year: 2022
  ident: 10.1016/j.jvssci.2025.100295_bib40
  article-title: Depletion of CD206(+) M2-like macrophages induces fibro-adipogenic progenitors activation and muscle regeneration
  publication-title: Nat Commun
  doi: 10.1038/s41467-022-34191-y
– volume: 2012
  year: 2012
  ident: 10.1016/j.jvssci.2025.100295_bib14
  article-title: Intermuscular adipose tissue is muscle specific and associated with poor functional performance
  publication-title: J Aging Res
  doi: 10.1155/2012/172957
– volume: 9
  start-page: 3670
  issue: 1
  year: 2018
  ident: 10.1016/j.jvssci.2025.100295_bib30
  article-title: Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy
  publication-title: Nat Commun
  doi: 10.1038/s41467-018-06068-6
– volume: 40
  start-page: 2577
  issue: 11
  year: 2020
  ident: 10.1016/j.jvssci.2025.100295_bib8
  article-title: Skeletal Muscle Pathology in Peripheral Artery Disease: A Brief Review
  publication-title: Arterioscler Thromb Vasc Biol
  doi: 10.1161/ATVBAHA.120.313831
– volume: 8
  start-page: 19
  issue: 1
  year: 2023
  ident: 10.1016/j.jvssci.2025.100295_bib20
  article-title: Odd skipped-related 1 controls the pro-regenerative response of fibro-adipogenic progenitors
  publication-title: NPJ Regen Med
  doi: 10.1038/s41536-023-00291-6
– volume: 21
  start-page: 786
  issue: 7
  year: 2015
  ident: 10.1016/j.jvssci.2025.100295_bib21
  article-title: Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors
  publication-title: Nat Med
  doi: 10.1038/nm.3869
– volume: 69
  start-page: 3S
  issue: 6s
  year: 2019
  ident: 10.1016/j.jvssci.2025.100295_bib2
  article-title: Global vascular guidelines on the management of chronic limb-threatening ischemia
  publication-title: J Vasc Surg
  doi: 10.1016/j.jvs.2019.02.016
– volume: 3
  issue: 21
  year: 2018
  ident: 10.1016/j.jvssci.2025.100295_bib10
  article-title: Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants
  publication-title: JCI Insight
  doi: 10.1172/jci.insight.123235
– volume: 31
  issue: 5
  year: 2020
  ident: 10.1016/j.jvssci.2025.100295_bib23
  article-title: Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles
  publication-title: Cell Rep
  doi: 10.1016/j.celrep.2020.107597
– volume: 10
  start-page: 19
  issue: 1
  year: 2020
  ident: 10.1016/j.jvssci.2025.100295_bib37
  article-title: A reference single-cell transcriptomic atlas of human skeletal muscle tissue reveals bifurcated muscle stem cell populations
  publication-title: Skelet Muscle
  doi: 10.1186/s13395-020-00236-3
– volume: 27
  start-page: 2029
  issue: 7
  year: 2019
  ident: 10.1016/j.jvssci.2025.100295_bib19
  article-title: Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle
  publication-title: Cell Rep
  doi: 10.1016/j.celrep.2019.04.074
– volume: 64
  start-page: 1101
  issue: 4
  year: 2016
  ident: 10.1016/j.jvssci.2025.100295_bib28
  article-title: Subacute limb ischemia induces skeletal muscle injury in genetically susceptible mice independent of vascular density
  publication-title: J Vasc Surg
  doi: 10.1016/j.jvs.2015.06.139
– volume: 130
  start-page: 127
  issue: 3
  year: 2016
  ident: 10.1016/j.jvssci.2025.100295_bib41
  article-title: Evaluation of the clinical relevance and limitations of current pre-clinical models of peripheral artery disease
  publication-title: Clin Sci (Lond)
  doi: 10.1042/CS20150435
– volume: 6
  start-page: 111
  issue: 1
  year: 2023
  ident: 10.1016/j.jvssci.2025.100295_bib24
  article-title: MME(+) fibro-adipogenic progenitors are the dominant adipogenic population during fatty infiltration in human skeletal muscle
  publication-title: Commun Biol
  doi: 10.1038/s42003-023-04504-y
– volume: 10
  issue: 3
  year: 2021
  ident: 10.1016/j.jvssci.2025.100295_bib33
  article-title: Unique Metabolomic Profile of Skeletal Muscle in Chronic Limb Threatening Ischemia
  publication-title: J Clin Med
  doi: 10.3390/jcm10030548
– volume: 387
  start-page: 2305
  issue: 25
  year: 2022
  ident: 10.1016/j.jvssci.2025.100295_bib3
  article-title: Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia
  publication-title: N Engl J Med
  doi: 10.1056/NEJMoa2207899
– volume: 117
  start-page: 1207
  issue: 9
  year: 2008
  ident: 10.1016/j.jvssci.2025.100295_bib27
  article-title: A quantitative trait locus (LSq-1) on mouse chromosome 7 is linked to the absence of tissue loss after surgical hindlimb ischemia
  publication-title: Circulation
  doi: 10.1161/CIRCULATIONAHA.107.736447
– volume: 15
  start-page: 459
  issue: 6
  year: 2024
  ident: 10.1016/j.jvssci.2025.100295_bib42
  article-title: Transcriptome profiling of fast/glycolytic and slow/oxidative muscle fibers in aging and obesity
  publication-title: Cell Death Dis
  doi: 10.1038/s41419-024-06851-y
– volume: 9
  issue: 12
  year: 2020
  ident: 10.1016/j.jvssci.2025.100295_bib9
  article-title: Fibrosis Distinguishes Critical Limb Ischemia Patients from Claudicants in a Transcriptomic and Histologic Analysis
  publication-title: J Clin Med
  doi: 10.3390/jcm9123974
– volume: 72
  start-page: 2006
  issue: 6
  year: 2020
  ident: 10.1016/j.jvssci.2025.100295_bib16
  article-title: Effect of muscle depletion on survival in peripheral arterial occlusive disease: Quality over quantity
  publication-title: J Vasc Surg
  doi: 10.1016/j.jvs.2020.03.050
– volume: 12
  start-page: 153
  issue: 2
  year: 2010
  ident: 10.1016/j.jvssci.2025.100295_bib17
  article-title: Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis
  publication-title: Nat Cell Biol
  doi: 10.1038/ncb2015
– volume: 305
  start-page: R291
  issue: 3
  year: 2013
  ident: 10.1016/j.jvssci.2025.100295_bib11
  article-title: Morphometric analysis of gastrocnemius muscle biopsies from patients with peripheral arterial disease: objective grading of muscle degeneration
  publication-title: Am J Physiol Regul Integr Comp Physiol
  doi: 10.1152/ajpregu.00525.2012
SSID ssj0002513285
Score 2.2988942
SourceID crossref
SourceType Index Database
StartPage 100295
Title Vcam1+ Fibro-adipogenic Progenitors Mark Fatty Infiltration in Chronic Limb Threatening Ischemia
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT9wwELZaKlVcEH0gHi3ygdvKqzy8WXKEihVUohLqgvaWjpMxZAVZBBsE_HrGdl48hKCXKGtZ3iTzZWY8-WaGsS0PfU04AaEUSCElxCKWYShwiGTRUw-D1OQ7H_6J9o_l78lg0n7Bt9klc9VP71_MK_kfqdIYydVkyb5Dss2iNEDnJF86koTp-CYZn6RwQZpotzeiTe9MQJZfzmiyYbtf2RPbSsek4_RGMCd3-6DQ-XlVKNfm-7nSuCbNSfXGZ8aBRBsoOaBNL17k8Mh3PfkrGuJqZTnbQLdlBRyVxfUZVsbQhunrb_rF6W3e4HBSWs1f4l3ZgnOEjlgAuWF3dKMRwaDhwlVKi-x9JMKB55QWvjDmFKWp_Oq6az7T4S6cMO1Pb67pXvrmX_rt9Mcls5-YsoZgWHPXpolbJTGrJG6Vj-xTQHuKsBPaMWabHL0wsC1cm-utUy0tH_D55XRcmY5PMl5mS9Vmgu84ZHxhH7D4yj4fVnSJb-yfBUiPP4UH78CDG3hwCw_ehQfPC17Bgxt48A48eA2P7-x4tDf-tS-qlhoiJZM4EKnWXpj5cjhErdIo9rXEbanpPQUfI4jJgQTTEQvIcwQVoQeZlF6gpcp0KHUarrCFYlbgKuN-bAoXSV8GWskh4LYC8INM0y8kuyHXmKifTnLpKqckr4ll_Z3zN9hiC8AfbGF-VeJPchDnatMGVjateB8A3pFnFw
linkProvider National Library of Medicine
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Vcam1%2B+Fibro-adipogenic+Progenitors+Mark+Fatty+Infiltration+in+Chronic+Limb+Threatening+Ischemia&rft.jtitle=JVS-vascular+science&rft.au=Dai%2C+Qunsheng&rft.au=Wan%2C+Changxin&rft.au=Xu%2C+Yueyuan&rft.au=Fei%2C+Kaileen&rft.date=2025-08-01&rft.issn=2666-3503&rft.eissn=2666-3503&rft.spage=100295&rft_id=info:doi/10.1016%2Fj.jvssci.2025.100295&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_jvssci_2025_100295
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2666-3503&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2666-3503&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2666-3503&client=summon