Central Injection of Substance P Antagonizes the RF Amide-Related Peptide-3 Impacts on Hypothalamic KISS-1 and GnRH Gene Expressions in Male Wistar Rats

Background: Gonadotropin-inhibitory hormone and its mammalian orthologues (RFRP: RF amid related peptide) are known to inhibit the secretion of gonadotropins. In addition, substance P (SP) a member of tachykinin’s family is demonstrated that can increase the firing rate of kisspeptin/neurokinin B/dy...

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Bibliographic Details
Published inInternational journal of basic science in medicine Vol. 3; no. 3; pp. 127 - 132
Main Authors Rahdar, Parastoo, Khazali, Homayoun
Format Journal Article
LanguageEnglish
Published Zabol University of Medical sciences 26.09.2018
Subjects
GnRH
KISS-1
Rat
RF amid-related peptid-3
Substance P
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