Serum 3'-sulfo-Lea indication of gastric cancer metastasis

• Published in: Clinica chimica acta Vol. 405; no. 1-2; pp. 119 - 126
• Main Authors: Zheng, Jing, Bao, Wei Qi, Sheng, Wei Qi, Guo, Lin, Zhang, Huan Le, Wu, Li Hui, Wu, Xing Zhong
• Format: Journal Article
• Language: English
• Published: Netherlands 01.07.2009
• Subjects: Adult; Aged; Aged, 80 and over; Amino Acid Sequence; Biomarkers, Tumor - blood; Cell Adhesion - drug effects; Cell Movement - drug effects; Cells, Cultured; Down-Regulation - drug effects; Female; Fluorouracil - pharmacology; Humans; Male; Middle Aged; Neoplasm Metastasis - pathology; Oligosaccharides - blood; Peptides - chemistry; Peptides - pharmacology; Stomach Neoplasms - blood; Stomach Neoplasms - pathology

3'-Sulfo-Le(a) is known to be the potent ligand of E-selectin which is important in cell adhesion and migration. Yet the significance of serum 3'-sulfo-Le(a) has not been explored and reported. Serum 3'-sulfo-Le(a) was analyzed by enzyme-linked immunosorbent assay. SPSS software was u...