Purication of betulinic acid from Eugenia florida (Myrtaceae) by high-speed counter-current chromatography

• Published in: Phytochemical analysis Vol. 16; no. 6; pp. 411 - 414
• Main Authors: Frighetto, Nelson, Welendorf, Rodolfo Max, da Silva, Ana Maria Pereira, Nakamura, Marcos Jun, Siani, Antonio Carlos
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.11.2005
• Subjects: betulinic acid; Counter-current chromatography; Eugenia florida

A high yield of betulinic acid (up to 17% from the ethanolic extract) was found in the leaves of Eugenia florida collected in south‐eastern Brazil, making this species a potential commercial source of the title compound. Extracts of E. florida were subjected to solvent partition, and rapid high‐spee...