TRANSLATIONAL MEDICINE: DEFINITION, HISTORY, AND STRATEGIES

What is translational medicine? This discipline, although defined differently by various groups in academia, regulatory institutions, and industry, shares the fundamental vision of translational medicine, which is to efficiently and effectively translate basic scientific findings relevant to human d...

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Bibliographic Details
Published inTranslational Medicine and Drug Discovery pp. 3 - 34
Main Author Littman, Bruce H.
Format Book Chapter
LanguageEnglish
Published Cambridge University Press 31.01.2011
Subjects
Pharmaceuticals
Pharmaceuticals, Cosmetics & Toiletries
Online AccessGet full text
ISBN9780521886451
9781107435940
1107435943
0521886457
DOI10.1017/CBO9780511976087.003

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Table of Contents:
  • 1.1 Biomarkers in Drug Development: A Common Understanding 1.2 Pharmacology: Testing the Target (POM) 1.3 Study Design Considerations for POM 1.4 Confirming the Hypothesis That a Drug Target (Mechanism of Action) Will Be Efficacious (POC) 1.5 Study Design Considerations for POC 1.6 Human Indications Screening 1.7 Commercial Profile and Translational Medicine 1.8 Conclusion 1.9 References