FT596: Translation of First-of-Kind Multi-Antigen Targeted Off-the-Shelf CAR-NK Cell with Engineered Persistence for the Treatment of B Cell Malignancies

• Published in: Blood Vol. 134; no. Supplement_1; p. 301
• Main Authors: Goodridge, Jode P, Mahmood, Sajid, Zhu, Huang, Gaidarova, Svetlana, Blum, Robert, Bjordahl, Ryan, Cichocki, Frank, Chu, Hui-yi, Bonello, Greg, Lee, Tom, Groff, Brian, Meza, Miguel, Walcheck, Bruce, Malmberg, Karl-Johan, Miller, Jeffrey S., Kaufman, Dan S, Valamehr, Bahram
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 13.11.2019

Induced pluripotent stem cell (iPSC)-derived effector cells offer distinct advantages for immune therapy over existing patient- or donor- derived platforms, both in terms of scalable manufacturing from a renewable starting cellular material and precision genetic engineering that is performed at the...