OP0025 CD209+/CD14+ DENDRITIC CELLS ARE ENRICHED AND ACTIVATED AT THE SITE OF INFLAMMATION AND ARE MODULATED BY JAK/STAT SIGNALLING

• Published in: Annals of the rheumatic diseases Vol. 80; no. Suppl 1; p. 14
• Main Authors: Marzaioli, V., Floudas, A., Canavan, M., Wade, S., Murray, K., Mullan, R., Veale, D., Fearon, U.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier B.V 01.06.2021; Elsevier Limited
• Subjects: Antigen-presenting cells; Arthritis; CC chemokine receptors; CCR6 protein; CCR7 protein; CD14 antigen; CD19 antigen; CD3 antigen; CD40 antigen; CD56 antigen; CD80 antigen; Cell differentiation; Cell surface; Chemokine receptors; Chemokines; CpG islands; CXCR3 protein; CXCR4 protein; CXCR5 protein; Dendritic cells; Flow cytometry; Inflammation; Interleukin 1; Interleukin 12; Interleukin 4; Interleukin 6; Phenotypes; Population

Dendritic cells (DCs) are a heterogeneous population of professional antigen-presenting cells which are at the interface between innate and adaptive immunity. A specific subset of DCs is known to derive from monocyte and has a key role in inflammation and infection. This study aimed to characterize...