POS0392 PRESENCE OF FOUR SERUM AUTOANTIBODIES ASSOCIATES WITH THE ACPA STATUS IN EARLY RHEUMATOID ARTHRITIS

• Published in: Annals of the rheumatic diseases Vol. 80; no. Suppl 1; pp. 425 - 426
• Main Authors: Lourido, L., Ruiz-Romero, C., Collado, L., Hansson, M., Klareskog, L., Sjöberg, R., Pin, E., Nilsson, P., Blanco, F.J.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier B.V 01.06.2021; Elsevier Limited
• Subjects: Antigens; Arrays; Autoantibodies; Citrulline; Diagnosis; Epidemiology; Immunoglobulin A; Immunoglobulin G; Kinases; MAP kinase; Pathogenesis; Patients; Protein arrays; Protein kinase; Proteins; Rheumatoid arthritis

The presence of anti-citrullinated protein antibodies (ACPAs) is a hallmark of rheumatoid arthritis (RA) that precede the development of the disease by years and is used for its clinical diagnosis. However, there are RA subjects that test negative for ACPA and thus the early diagnosis on these patie...