Research advances on silence information regulator 6 as a potential therapeutic target for bone regeneration and repair

• Published in: Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban Vol. 53; no. 4; pp. 427 - 433
• Main Authors: PAN, Wenzheng, HE, Yong, HUANG, Yue
• Format: Journal Article
• Language: English
• Published: China 25.08.2024
• Subjects: Animals; Bone Regeneration; Cell Differentiation; Humans; NF-kappa B - metabolism; Osteoblasts; Osteoclasts; Osteogenesis; Signal Transduction; Sirtuins - metabolism; Review; Repair; Bone regeneration; Bone metabolism; Silence information regulator 6

Segmental bone defects and nonunion of fractures caused by trauma, infection, tumor or systemic diseases with limited osteogenesis and prolonged bone healing cycles are challenging issues in orthopedic clinical practice. Therefore, identifying regulatory factors for bone tissue regeneration and meta...