Association of R-loop binding proteins with prognosis and anti-tumor drug sensitivity in lung adenocarcinoma: a bioinfor-matic study

• Published in: Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban Vol. 53; no. 4; pp. 472 - 480
• Main Authors: WANG, Tingye, DING, Yanlin, TAO, Li
• Format: Journal Article
• Language: English
• Published: China 25.08.2024
• Subjects: Adenocarcinoma of Lung - drug therapy; Adenocarcinoma of Lung - genetics; Antineoplastic Agents - therapeutic use; Drug Resistance, Neoplasm - genetics; Humans; Lung Neoplasms - drug therapy; Lung Neoplasms - genetics; Prognosis; Predicting model; R-loop binding protein; Drug susceptibility; Lung adenocarcinoma; Prognostic factors

To investigate the association of R-loop binding proteins with prognosis and chemotherapy efficacy in lung adenocarcinoma. The data related to R-loop regulatory genes were obtained from literature of R-loop proteomics and relevant databases. We used 403 cases of lung adenocarcinoma in the Cancer Gen...