P06.06 A mutation-specific vaccine for Histone-3 K27M-mutated gliomas

• Published in: Neuro-oncology (Charlottesville, Va.) Vol. 19; no. suppl_3; p. iii50
• Main Authors: Ochs, K., Ott, M., Bunse, T., Sahm, F., Bunse, L., Keil, M., Deumelandt, K., Sonner, J., von Deimling, A., Wick, W., Platten, M.
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 01.05.2017
• Subjects: POSTER PRESENTATIONS

Contrary to the assumption that brain tumors are hardly immunogenic, immunotherapeutic approaches such as antigen-specific vaccines have become increasingly relevant in clinical trials for malignant gliomas. For instance, a point mutation in the gene for isocitrate dehydrogenase type 1 frequently pr...