Synapsis and DNA cleavage in  C31 integrase-mediated site-specific recombination

• Published in: Nucleic acids research Vol. 32; no. 8; pp. 2607 - 2617
• Main Author: Smith, M. C. A.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford Publishing Limited (England) 28.04.2004

The Streptomyces phage [straight phi]C31 encodes an integrase belonging to the serine recombinase family of site-specific recombinases. The well studied serine recombinases, the resolvase/invertases, bring two recombination sites together in a synapse, and then catalyse a concerted four-strand stagg...