Risk of severe immune-related adverse events in cancer patients with pre-existing autoimmunity receiving immune checkpoint inhibitor therapy

• Published in: Current cancer reports Vol. 5; no. 1; p. 168
• Main Authors: Isaacs, Dayna Jill, Kathuria-Prakash, Nikhita, Hilder, Robin, Lechner, Melissa G, Drakaki, Alexandra
• Format: Journal Article
• Language: English
• Published: Singapore 20.02.2024
• Subjects: immune checkpoint inhibitor; cancer; autoimmunity; immune related adverse events

To evaluate the frequency and severity of irAEs in patients with pre-existing autoimmunity, including irAE-related morbidity and mortality, irAE-related management and resolution, and outcome of ICI rechallenge, to better understand the treatment options for this vulnerable patient population. We de...