46. Tacrolimus Increases Susceptibility to Secondary Infection in a Mouse Model

• Published in: Open forum infectious diseases Vol. 7; no. Supplement_1; p. S24
• Main Authors: Miller-Handley, Hilary, Kinder, Jeremy, Pham, Giang, Way, Sing Sing
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 31.12.2020
• Subjects: Oral Abstracts

Abstract Background Transplant acceptance requires life-long pharmacological intervention that broadly suppresses recipients’ immunity in order to prevent rejection of foreign graft. In turn, non-specific immune-suppression in these patients is also associated with increased risk of infection from o...