Different Subsets of Haematopoietic Cells and Immune Cells in Bone Marrow between Young and Old Donors

• Published in: Blood Vol. 136; no. Supplement 1; pp. 33 - 34
• Main Authors: Yao, Weili, Wen, Qi, Zhao, Hong-Yan, Zhang, Yuan-Yuan, Tang, Shuqian, Wang, Yu, Xu, Lan-Ping, Zhang, Xiao-Hui, Huang, Xiao Jun, Kong, Yuan
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 05.11.2020

Background Young donors are reported to be associated with better transplant outcomes than old donors in allo-HSCT, but the underlying mechanism is still uncertain. Successful allo-HSCT relies on the rapid reconstitution of donor-derived haematopoietic and immune systems in the recipient. Therefore,...