Clinical Features and Cytoreduction Therapy in Children with Newly Diagnosed Acute Myeloid Leukemia and Hyperleukocytosis

• Published in: Blood Vol. 138; no. Supplement 1; p. 2295
• Main Authors: Christakopoulos, Georgios E., Walker, Kendra N, Wang, Lei, Takemoto, Clifford, Zheng, Yan, Pui, Ching-Hon, Ribeiro, Raul C, Pounds, Stanley B, Rubnitz, Jeffrey E., Inaba, Hiroto
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 23.11.2021

Background Hyperleukocytosis is observed in 5% to 20% of patients with newly diagnosed acute myeloid leukemia (AML) and is associated with an increased risk of early complications and mortality. While being used frequently in patients with AML and hyperleukocytosis, the clinical utility of leukapher...