Quality and safety evaluation of a Ghanaian polyherbal product EAF-2011 for the management of superficial mycoses

• Published in: International journal of medicine and biomedical research Vol. 2; no. 2; pp. 91 - 102
• Main Authors: Dickson, R.A, Mensah, M.L.K, Thomford, K.P, Annan, K, Mills-Robertson, F.C, Appiah, A.A, Quarshie, O, Antwi, S, Kaminta, S, Edoh, D
• Format: Journal Article
• Language: English
• Published: Lagos Michael Joanna Publications 16.08.2013
• Subjects: Alkaloids
• DOI: 10.14194/ijmbr.222
• ISSN: 2277-0941

The widespread use of herbal medicines in recent years means that issues concerning their quality, safety and efficacy need to be answered. In the current study, the polyherbal formulation EAF-2011 used in the Centre for Scientific Research into Plant Medicine, Mampong-Akwapemfor the management of superficial mycoses was evaluated for its quality and safety. The study sought to evaluate the quality and safety of the product in the management of superficial mycoses. The method of standardisation using the basic phytochemical screening and the thin layer chromatography procedures was used. The product demonstrated stability during the study period of one year as results obtained from the thin layer chromatography, physicochemical and biological assay did not indicate any significant change in characteristics. Alkaloids, phenols, flavonoids, sterols and triterpenes were detected in the product. Three spots obtained by the thin layer chromatography were shown to be ideal for use as analytical markers for the product.