The effect of intra- and inter-fractional motion on target coverage and margins in proton therapy for uveal melanoma

• Published in: Physics in medicine & biology Vol. 69; no. 21; pp. 215038 - 215051
• Main Authors: Björkman, Daniel, Via, Riccardo, Lomax, Antony, De Prado, Maria, Baroni, Guido, Weber, D C, Hrbacek, Jan
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 30.10.2024
• Subjects: intra-ocular tumours; peri-tumourial margins; radiotherapy; treatment planning; Radiotherapy; Treatment planning; Intra-ocular tumors; Peri-tumoral margins

This study aims to assess the effective lateral margin requirements for target coverage in ocular proton therapy (OPT), considering the unique challenges posed by eye motion and hypofractionation. It specifically addresses the previously unaccounted-for uncertainty contribution of intra-fractional m...