Myocardial work index and myofilament calcium sensitivity: possible hand in hand markers of contractility in aortic valve stenosis patients - a translational study

• Published in: European heart journal Vol. 44; no. Supplement_2
• Main Authors: Ladanyi, Z, Ruppert, M, Fabian, A, Ujvari, A, Bodi, B, Papp, Z, Radovits, T, Sayour, A A, Molnar, L, Straub, E, Nagy, A, Kovacs, A, Lakatos, B K, Merkely, B
• Format: Journal Article
• Language: English
• Published: 09.11.2023

Abstract Background In aortic valve stenosis, conventional echocardiographic parameters, such as ejection fraction (EF), are heavily influenced by the increased afterload caused by the valvular disease. Myocardial work index (GWI) quantifies myocardial deformation depending on the momentary LV press...