Effects of PEEP and IRV on Blood Gases in Children under General Anesthesia

The effects of inverse ratio ventilation (IRV) is controvertial. There are few reports with respect to IRV in children. In 20 healthy children with body weight below 20kg IRV and positive end-expiratory pressure ventilation (PEEP) was performed during urological surgery under fentanyl-nitrous oxide-...

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Published inNihon Rinshō Masui Gakkai shi Vol. 7; no. 4; pp. 437 - 440
Main Authors MORISAKI, Hiroshi, SUZUKI, Gen'ichi, MIYAZAWA, Noriko, KIICHI, Yukou, MISAKI, Toru, SUZUKI, Atsuko
Format Journal Article
LanguageEnglish
Published THE JAPAN SOCIETY FOR CLINICAL ANESTHESIA 15.07.1987
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Abstract The effects of inverse ratio ventilation (IRV) is controvertial. There are few reports with respect to IRV in children. In 20 healthy children with body weight below 20kg IRV and positive end-expiratory pressure ventilation (PEEP) was performed during urological surgery under fentanyl-nitrous oxide-oxygen anesthesia. We analysed arterial and mixed venous blood gases and caluculated oxygen content difference and intrapulmonary shunt. IRV and PEEP were not effective on gas exchange parameters during the whole procedure except the value of PaCO2 in the group IRV (1.7:1) FIO2 0.5. No remarkable influence on circulation was also observed in the all studied groups. Ineffectiveness of IRV and PEEP partly came from that the subjects were healthy children with enough reserved function in cardio-respiratory systems. Other reasons would be many factors during operation such as surgical stimuli, general anesthesia influenced on the pulmonary circulation.
AbstractList The effects of inverse ratio ventilation (IRV) is controvertial. There are few reports with respect to IRV in children. In 20 healthy children with body weight below 20kg IRV and positive end-expiratory pressure ventilation (PEEP) was performed during urological surgery under fentanyl-nitrous oxide-oxygen anesthesia. We analysed arterial and mixed venous blood gases and caluculated oxygen content difference and intrapulmonary shunt. IRV and PEEP were not effective on gas exchange parameters during the whole procedure except the value of PaCO2 in the group IRV (1.7:1) FIO2 0.5. No remarkable influence on circulation was also observed in the all studied groups. Ineffectiveness of IRV and PEEP partly came from that the subjects were healthy children with enough reserved function in cardio-respiratory systems. Other reasons would be many factors during operation such as surgical stimuli, general anesthesia influenced on the pulmonary circulation.
Author KIICHI, Yukou
SUZUKI, Gen'ichi
SUZUKI, Atsuko
MISAKI, Toru
MORISAKI, Hiroshi
MIYAZAWA, Noriko
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  fullname: SUZUKI, Atsuko
  organization: Tokyo Metropolitan Kiyose Children's Hospital Department of Anesthesia
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References 4) Fuleihan SF, Wilson RS, Pontoppidan H: Effect of mechanical ventilation with end-inspiratory pause on blood-gas exchange. Anesth Analg 55: 122-130, 1976
6) Reynolds EOR, Taghizadeh A: Improved prognosis of infants mechanically ventilated for hyaline membrane disease. Arch Dis Child 49: 505-515, 1974
3) Perez-Chada RD, Cardaz JP, Madgwick RG, et al.: Cardiopulmonary effects of an inspiratory hold and continuous positive pressure ventilation in goats. Intensive Care Med 9: 263-269, 1983
8) Osswald PM, Hartimg HJ, Klose R, et al.: The effect of prolonged inspiration time and PEEP on compliance and gas exchange in ventilated patients. Anaesthesist 30: 71-76, 1981
5) Berman LS, Downs JB, Eeden AV, et al.: Inspiration: expiration is mean airway pressure the differance? Crit Care Med 9: 775-777, 1981
7) Froese AB, Bryan AC: Effects of anesthesia and paralysis on diaphragmatic mechanics in man. Anesthesiology 41: 242-255, 1974
2) Cole AGH, Weller SF, Sykes MK: Inverse ratio ventilation compared with PEEP in adult respiratory failure. Intensive Care Med 10: 227-232, 1984
1) Knelson JH, Howatt WF, DeMuth GR: Effect of respiratory pattern on alveolar gas exchange. J Appl Physiol 29: 328-331, 1970
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Title Effects of PEEP and IRV on Blood Gases in Children under General Anesthesia
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