Survival outcomes of adjuvant treatment in upstaged clinical T2N0 rectal cancer: are we underutilizing therapy?

• Published in: Journal of gastrointestinal surgery p. 101869
• Main Authors: Kripalani, Simran, Westwood, Caroline, Hasler, Jill S., Wookey, Vanessa, Porpiglia, Andrea S., Greco, Stephanie H., Reddy, Sanjay S., Meyer, Joshua E., Farma, Jeffrey M., Villano, Anthony M.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 28.10.2024
• Subjects: Adjuvant treatment; Clinical T2N0; National Cancer Database; Rectal cancer; National Cancer Database; Rectal cancer; Clinical T2N0; Adjuvant treatment

Patients with rectal cancer staged as clinical T2N0 (cT2N0) are recommended to undergo upfront resection. However, when the tumor is subsequently upstaged to pathologic T3N0 (pT3N0), there are no clear guidelines for adjuvant treatment. This study aimed to analyze national trends in adjuvant managem...