Calibration of T 2 oximetry MRI for subjects with sickle cell disease

• Published in: Magnetic resonance in medicine Vol. 86; no. 2; pp. 1019 - 1028
• Main Authors: Bush, Adam, Vu, Chau, Choi, Soyoung, Borzage, Matthew, Miao, Xin, Li, Wenbo, Qin, Qin, Nederveen, Aart J., Coates, Thomas D., Wood, John C.
• Format: Journal Article
• Language: English
• Published: United States 01.08.2021
• Subjects: Anemia, Sickle Cell - diagnostic imaging; Calibration; Humans; Magnetic Resonance Imaging; Oximetry; Oxygen; calibration; T2 oximetry; venous saturation; sickle cell disease

Cerebral T oximetry is a non-invasive imaging method to measure blood T and cerebral venous oxygenation. Measured T values are converted to oximetry estimates using carefully validated and potentially disease-specific calibrations. In sickle cell disease, red blood cells have abnormal cell shape and...