Effect of low vs high intraoperative fraction of inspired oxygen on postoperative organ complications: a systematic review and meta-analysis of randomized controlled trials

• Published in: ANESTHESIOLOGY AND PERIOPERATIVE SCIENCE Vol. 3; no. 3
• Main Authors: Li, Xuefei, Han, Yang, Zhuang, Huijia, Jiang, Jiali, Sun, Qirong, Yu, Hai
• Format: Journal Article
• Language: English
• Published: Singapore Springer Nature Singapore 26.08.2025
• Subjects: Anesthesiology; Critical Care Medicine; Intensive; Medicine; Medicine & Public Health; Neurosciences; Pharmacology/Toxicology; Review Article; Surgery; Fraction of inspired oxygen; Organ complications; Surgery; Postoperative complications

Purpose Intraoperative supplemental oxygen may induce postoperative organ complications by aggravating oxidative stress and vasoconstriction. This meta-analysis was to determine whether the higher fraction of inspired oxygen (FiO 2 ) would increase the risk of organ complications among patients unde...