Dissolved 129 Xe lung MRI with four‐echo 3D radial spectroscopic imaging: Quantification of regional gas transfer in idiopathic pulmonary fibrosis

• Published in: Magnetic resonance in medicine Vol. 85; no. 5; pp. 2622 - 2633
• Main Authors: Collier, Guilhem J., Eaden, James A., Hughes, Paul J. C., Bianchi, Stephen M., Stewart, Neil J., Weatherley, Nicholas D., Norquay, Graham, Schulte, Rolf F., Wild, Jim M.
• Format: Journal Article
• Language: English
• Published: United States 01.05.2021
• Subjects: Humans; Idiopathic Pulmonary Fibrosis - diagnostic imaging; Lung - diagnostic imaging; Magnetic Resonance Imaging; Spectrum Analysis; Xenon; Xenon Isotopes; lung; spectroscopic imaging; hyperpolarized 129Xe; IPF

Imaging of the different resonances of dissolved hyperpolarized xenon-129 ( Xe) in the lung is performed using a four-echo flyback 3D radial spectroscopic imaging technique and is evaluated in healthy volunteers (HV) and subjects with idiopathic pulmonary fibrosis (IPF). 10 HV and 25 subjects with I...