Portal hemodynamic changes after hepatocyte transplantation in acute hepatic failure

• Published in: Journal of biomedical science Vol. 11; no. 6; pp. 756 - 763
• Main Authors: Yu, Chun-Hsien, Chen, Hui-Ling, Chen, Wei-Tsung, Ni, Yen-Hsuan, Lin, Yah-Luen, Chang, Mei-Hwei
• Format: Journal Article
• Language: English
• Published: England 01.11.2004
• Subjects: Animals; Cell Transplantation - methods; Cells, Cultured; Galactosamine - pharmacology; Hepatocytes - cytology; Hepatocytes - metabolism; Hypertension, Portal - pathology; Liver - injuries; Liver Failure; Liver Failure, Acute - therapy; Liver Transplantation - methods; Portal Pressure; Pressure; Rats; Rats, Inbred F344; Time Factors

Hepatocyte transplantation has been proposed as an alternative for rescuing patients with acute hepatic failure. However, portal hemodynamic changes and issues of safety after hepatocyte transplantation in acute hepatic failure have not been systemically evaluated because of the lack of a suitable e...