Profil de sensibilité aux antibiotiques des souches de Pseudomonas aeruginosa isolées dans la région de Monastir
Le but de cette étude est d’évaluer l’activité des antibiotiques les plus fréquemment prescris vis-à-vis des souches de Pseudomonas aeruginosa isolées de 2002 à 2005 dans un CHU tunisien. L’étude de la sensibilité aux antibiotiques a été réalisée par la méthode de diffusion en milieu gélosé selon le...
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Published in | Médecine et maladies infectieuses Vol. 38; no. 10; pp. 554 - 556 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | French |
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Elsevier SAS
01.10.2008
Elsevier |
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Abstract | Le but de cette étude est d’évaluer l’activité des antibiotiques les plus fréquemment prescris vis-à-vis des souches de
Pseudomonas aeruginosa isolées de 2002 à 2005 dans un CHU tunisien. L’étude de la sensibilité aux antibiotiques a été réalisée par la méthode de diffusion en milieu gélosé selon les recommandations du CA-SFM. Cette étude a concerné 1368 souches de
P. aeruginosa isolées de pus, de prélèvements respiratoires, d’urines et d’hémocultures dans respectivement 52,9, 19,5, 10,6 et 5 % des cas. Les taux de résistance à la ticarcilline, céftazidime, imipénème, gentamicine, amikacine et ciprofloxacine ont été respectivement de 26,2, 21,8, 19,6, 39,3, 19,2 et 21,6 %. Afin d’améliorer le pronostic des infections graves à
P. aeruginosa, une surveillance régulière de la résistance aux antibiotiques de ces souches est nécessaire pour adapter les schémas thérapeutiques.
The aim of this study was to determine the susceptibility rates and patterns in
P. aeruginosa strains isolated from 2002 to 2005 in a teaching Hospital of Tunisia. Susceptibility to antibiotics was assessed according to CA-SFM guidelines. During this period, 1,368 strains of
P. aeruginosa were identified, they were isolated mainly from pus (52.9%), respiratory samples (19.5 %), urine (10.6%), and blood cultures (5%). The percentages of resistant isolates were as follows: ticarcilline: 26.2%; ceftazidime: 21.8%; imipenem: 19.6%; gentamicin: 39.3%; amikacin: 19.2%, and ciprofloxacin: 21.6%. Nosocomial infections in
P. aeruginosa are responsible for important morbidity and mortality rates, the survey of resistance to antibiotics is necessary for an efficient treatment. |
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AbstractList | Le but de cette étude est d’évaluer l’activité des antibiotiques les plus fréquemment prescris vis-à-vis des souches de
Pseudomonas aeruginosa isolées de 2002 à 2005 dans un CHU tunisien. L’étude de la sensibilité aux antibiotiques a été réalisée par la méthode de diffusion en milieu gélosé selon les recommandations du CA-SFM. Cette étude a concerné 1368 souches de
P. aeruginosa isolées de pus, de prélèvements respiratoires, d’urines et d’hémocultures dans respectivement 52,9, 19,5, 10,6 et 5 % des cas. Les taux de résistance à la ticarcilline, céftazidime, imipénème, gentamicine, amikacine et ciprofloxacine ont été respectivement de 26,2, 21,8, 19,6, 39,3, 19,2 et 21,6 %. Afin d’améliorer le pronostic des infections graves à
P. aeruginosa, une surveillance régulière de la résistance aux antibiotiques de ces souches est nécessaire pour adapter les schémas thérapeutiques.
The aim of this study was to determine the susceptibility rates and patterns in
P. aeruginosa strains isolated from 2002 to 2005 in a teaching Hospital of Tunisia. Susceptibility to antibiotics was assessed according to CA-SFM guidelines. During this period, 1,368 strains of
P. aeruginosa were identified, they were isolated mainly from pus (52.9%), respiratory samples (19.5 %), urine (10.6%), and blood cultures (5%). The percentages of resistant isolates were as follows: ticarcilline: 26.2%; ceftazidime: 21.8%; imipenem: 19.6%; gentamicin: 39.3%; amikacin: 19.2%, and ciprofloxacin: 21.6%. Nosocomial infections in
P. aeruginosa are responsible for important morbidity and mortality rates, the survey of resistance to antibiotics is necessary for an efficient treatment. |
Author | Khélifa, A. Ben Elhadj Mastouri, M. Sahnoun, O. Abdallah, H. Ben Elargoubi, A. Noomen, S. |
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Keywords | Pseudomonas aeruginosa Sensibilité aux antibiotiques Susceptibility to antibiotics Pseudomonadales Infection Microbiologie Antibactérien Pseudomonadaceae Sensibilité Bactérie Antibiotique Test sensibilité médicamenteuse |
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References | Friedland, Gallagher, King, Woods (bib7) 2004; 16 Cavallo, Hocquet, Plesiat, Fabre, Roussel-Delvallez (bib5) 2007; 59 Kalai, Jouaihia, Mahjoubi, Ghozzi, Thabet, Ben Redjeb (bib4) 2004; 82 Hanberger, Diekma, Fluit, Iones, Struelens, Spencer (bib10) 2001; 48 Husson, Hamze, Verhille, Izard (bib1) 2000 Hance, Fabre, Leblanc, Cavallo (bib8) 2001; 49 Nicoletti, Schito, Fadda, Boros, Nicolsi, Marchese (bib6) 2006; 18 Watine, Hassini, Cavallo (bib9) 2001; 49 Van Eldere (bib3) 2003; 51 Rio, Pina, Jurin, Allouch, Didion, Chardon (bib2) 2002; 50 Friedland (10.1016/j.medmal.2008.05.002_bib7) 2004; 16 Watine (10.1016/j.medmal.2008.05.002_bib9) 2001; 49 Hanberger (10.1016/j.medmal.2008.05.002_bib10) 2001; 48 Van Eldere (10.1016/j.medmal.2008.05.002_bib3) 2003; 51 Nicoletti (10.1016/j.medmal.2008.05.002_bib6) 2006; 18 Rio (10.1016/j.medmal.2008.05.002_bib2) 2002; 50 Kalai (10.1016/j.medmal.2008.05.002_bib4) 2004; 82 Cavallo (10.1016/j.medmal.2008.05.002_bib5) 2007; 59 Husson (10.1016/j.medmal.2008.05.002_bib1) 2000 Hance (10.1016/j.medmal.2008.05.002_bib8) 2001; 49 |
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SubjectTerms | Antibactériens Antibiotiques. Antiinfectieux. Antiparasitaires Pathologie infectieuse Pharmacologie. Traitements medicamenteux Pseudomonas aeruginosa Sciences biologiques et medicales Sciences medicales Sensibilité aux antibiotiques Susceptibility to antibiotics |
Title | Profil de sensibilité aux antibiotiques des souches de Pseudomonas aeruginosa isolées dans la région de Monastir |
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