Profil de sensibilité aux antibiotiques des souches de Pseudomonas aeruginosa isolées dans la région de Monastir

Le but de cette étude est d’évaluer l’activité des antibiotiques les plus fréquemment prescris vis-à-vis des souches de Pseudomonas aeruginosa isolées de 2002 à 2005 dans un CHU tunisien. L’étude de la sensibilité aux antibiotiques a été réalisée par la méthode de diffusion en milieu gélosé selon le...

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Published inMédecine et maladies infectieuses Vol. 38; no. 10; pp. 554 - 556
Main Authors Abdallah, H. Ben, Noomen, S., Khélifa, A. Ben Elhadj, Sahnoun, O., Elargoubi, A., Mastouri, M.
Format Journal Article
LanguageFrench
Published Paris Elsevier SAS 01.10.2008
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Abstract Le but de cette étude est d’évaluer l’activité des antibiotiques les plus fréquemment prescris vis-à-vis des souches de Pseudomonas aeruginosa isolées de 2002 à 2005 dans un CHU tunisien. L’étude de la sensibilité aux antibiotiques a été réalisée par la méthode de diffusion en milieu gélosé selon les recommandations du CA-SFM. Cette étude a concerné 1368 souches de P. aeruginosa isolées de pus, de prélèvements respiratoires, d’urines et d’hémocultures dans respectivement 52,9, 19,5, 10,6 et 5 % des cas. Les taux de résistance à la ticarcilline, céftazidime, imipénème, gentamicine, amikacine et ciprofloxacine ont été respectivement de 26,2, 21,8, 19,6, 39,3, 19,2 et 21,6 %. Afin d’améliorer le pronostic des infections graves à P. aeruginosa, une surveillance régulière de la résistance aux antibiotiques de ces souches est nécessaire pour adapter les schémas thérapeutiques. The aim of this study was to determine the susceptibility rates and patterns in P. aeruginosa strains isolated from 2002 to 2005 in a teaching Hospital of Tunisia. Susceptibility to antibiotics was assessed according to CA-SFM guidelines. During this period, 1,368 strains of P. aeruginosa were identified, they were isolated mainly from pus (52.9%), respiratory samples (19.5 %), urine (10.6%), and blood cultures (5%). The percentages of resistant isolates were as follows: ticarcilline: 26.2%; ceftazidime: 21.8%; imipenem: 19.6%; gentamicin: 39.3%; amikacin: 19.2%, and ciprofloxacin: 21.6%. Nosocomial infections in P. aeruginosa are responsible for important morbidity and mortality rates, the survey of resistance to antibiotics is necessary for an efficient treatment.
AbstractList Le but de cette étude est d’évaluer l’activité des antibiotiques les plus fréquemment prescris vis-à-vis des souches de Pseudomonas aeruginosa isolées de 2002 à 2005 dans un CHU tunisien. L’étude de la sensibilité aux antibiotiques a été réalisée par la méthode de diffusion en milieu gélosé selon les recommandations du CA-SFM. Cette étude a concerné 1368 souches de P. aeruginosa isolées de pus, de prélèvements respiratoires, d’urines et d’hémocultures dans respectivement 52,9, 19,5, 10,6 et 5 % des cas. Les taux de résistance à la ticarcilline, céftazidime, imipénème, gentamicine, amikacine et ciprofloxacine ont été respectivement de 26,2, 21,8, 19,6, 39,3, 19,2 et 21,6 %. Afin d’améliorer le pronostic des infections graves à P. aeruginosa, une surveillance régulière de la résistance aux antibiotiques de ces souches est nécessaire pour adapter les schémas thérapeutiques. The aim of this study was to determine the susceptibility rates and patterns in P. aeruginosa strains isolated from 2002 to 2005 in a teaching Hospital of Tunisia. Susceptibility to antibiotics was assessed according to CA-SFM guidelines. During this period, 1,368 strains of P. aeruginosa were identified, they were isolated mainly from pus (52.9%), respiratory samples (19.5 %), urine (10.6%), and blood cultures (5%). The percentages of resistant isolates were as follows: ticarcilline: 26.2%; ceftazidime: 21.8%; imipenem: 19.6%; gentamicin: 39.3%; amikacin: 19.2%, and ciprofloxacin: 21.6%. Nosocomial infections in P. aeruginosa are responsible for important morbidity and mortality rates, the survey of resistance to antibiotics is necessary for an efficient treatment.
Author Khélifa, A. Ben Elhadj
Mastouri, M.
Sahnoun, O.
Abdallah, H. Ben
Elargoubi, A.
Noomen, S.
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10.1053/jhin.2001.0987
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Keywords Pseudomonas aeruginosa
Sensibilité aux antibiotiques
Susceptibility to antibiotics
Pseudomonadales
Infection
Microbiologie
Antibactérien
Pseudomonadaceae
Sensibilité
Bactérie
Antibiotique
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Snippet Le but de cette étude est d’évaluer l’activité des antibiotiques les plus fréquemment prescris vis-à-vis des souches de Pseudomonas aeruginosa isolées de 2002...
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SubjectTerms Antibactériens
Antibiotiques. Antiinfectieux. Antiparasitaires
Pathologie infectieuse
Pharmacologie. Traitements medicamenteux
Pseudomonas aeruginosa
Sciences biologiques et medicales
Sciences medicales
Sensibilité aux antibiotiques
Susceptibility to antibiotics
Title Profil de sensibilité aux antibiotiques des souches de Pseudomonas aeruginosa isolées dans la région de Monastir
URI https://dx.doi.org/10.1016/j.medmal.2008.05.002
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