Enzyme inhibitor takes an unexpected approach toward blocking cancer-promoting protein

• Published in: Cancer biology & therapy Vol. 8; no. 19; pp. 1791 - 1790
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 01.10.2009

  Scientists at Fox Chase Cancer Center have discovered a unique method of attack that may be used to inhibit signaling enzymes called kinases, which often have a role in sustaining drug-resistant cancerous cells. They have confirmed that IPA-3, a small molecular inhibitor of a kinase called PAK1, t...