Aortic Stiffness is Negatively Associated with Microvascular Glycocalyx Thickness and Microvascular Perfusion among Older Adults: Role of Carotid Pressure Pulsatility

• Published in: The FASEB journal Vol. 36 Suppl 1
• Main Authors: Gimblet, Colin, Armstrong, Matthew, Nuckols, Virginia, Stroud, Amy K, Guerrero, Mariah, Pierce, Gary
• Format: Journal Article
• Language: English
• Published: United States 01.05.2022

The glycocalyx layer is essential to the maintenance of a healthy microvascular endothelium and diminishes with advancing age. Similarly, the aorta stiffens with aging and increases the risk of cardiovascular disease and target organ damage, possibly through pressure pulsatility-associated microvasc...