Dual COX-2/sEH Inhibition and Immune Checkpoint Blockade Regress Bladder Cancer Tumors in Mice

• Published in: The FASEB journal Vol. 36 Suppl 1
• Main Authors: Rothenberger, Eva, Wang, Weicang, Kipper, Franciele C, Kelly, Abigail, Hwang, Sung Hee, Duncan, Madeline, Bielenberg, Diane R, Henderson, Paul T, Cimino, George, Zimmermann, Maike, Hammock, Bruce D, Panigrahy, Dipak
• Format: Journal Article
• Language: English
• Published: United States 01.05.2022

Unresolved inflammation plays a critical role in bladder cancer initiation and progression. Acute inflammation leads to eicosanoid-driven cytokine production. Controlling the local and systemic inflammatory response in bladder cancer is critical to preventing bladder cancer progression. Chemotherapy...