miRNAs regulating gene expression/gene networks and its multifactorial pathways in open‐angle glaucoma

• Published in: Acta ophthalmologica (Oxford, England) Vol. 100; no. S275
• Main Authors: Blasco, Irene Andrés, Raga‐Cervera, Jorge, Bolarin, Jose M., Gallego‐Martinez, Alex, Sánchez, Javier Benítez‐Del‐Castillo, Pinazo‐Durán, Maria D., Zanón‐Moreno, Vicente
• Format: Journal Article
• Language: English
• Published: Malden Wiley Subscription Services, Inc 01.12.2022
• Subjects: Gene expression; Glaucoma; Metabolic pathways; MicroRNAs; miRNA; Next-generation sequencing; Signal transduction; Tears

Purpose: To describe the microRNAs (miRNAs) involved in ocular hypertension (OHT) and open‐angle glaucoma (OAG) to develop miRNA‐based glaucoma diagnostic and therapeutic tools. Methods: An analytical, observational, case–control study was performed in 42 volunteers of both sexes, aged 50 to 80 year...