1268. A retrospective observational study to evaluate the efficacy of antimicrobial time-out for optimizing the duration of antimicrobial administration in emergency abdominal surgery patients
Abstract Background Appropriate use of antibiotics is important for the prevention of antimicrobial-resistant organisms. However, prolonged administration of broad-spectrum antimicrobial agents is frequently used in surgery, especially in emergency surgery with infection. The low rate of the appropr...
Saved in:
Published in | Open forum infectious diseases Vol. 10; no. Supplement_2 |
---|---|
Main Authors | , |
Format | Journal Article |
Language | English |
Published |
US
Oxford University Press
27.11.2023
|
Online Access | Get full text |
Cover
Loading…
Abstract | Abstract
Background
Appropriate use of antibiotics is important for the prevention of antimicrobial-resistant organisms. However, prolonged administration of broad-spectrum antimicrobial agents is frequently used in surgery, especially in emergency surgery with infection. The low rate of the appropriate use of antimicrobial agents is regarded as a worldwide problem. In order to promote the proper use of antimicrobials, our department has administered daily antimicrobial time-outs to surgical patients as part of the Antimicrobial Stewardship Program since January 2018. This study investigates whether the Antimicrobial Time-out has led to appropriate use of antibiotics.
Methods
Patients aged 18 years and older who underwent emergency abdominal surgery in our department from May 2017 to August 2018 were included. Pre- and postoperative clinical information was extracted from the medical records.
Results
56 and 66 patients were treated before and after the introduction of antimicrobial time-out, respectively. The mean duration of antimicrobial use was 3.8 and 3.3 days before and after the introduction of antibiotic time-out. No significant difference was observed, but a 13.7% decrease was observed (P=0.51). Limiting the analysis to patients who received a minimum of two days of antimicrobial therapy, treated patients were 23 and 27, and the mean duration of antimicrobial use was 7.8 and 6.6 days(P=0.38) before and after the introduction of antibiotic time-out, respectively.
There were also no significant differences in the incidence of complications (Clavien-Dindo classification Grade II or higher) (28.6% vs. 25.8%, P=0.73) or length of hospital stay (17.2 vs. 14.0 days, P=0.38).
Conclusion
Antibiotic time-out in surgical practice may contribute to a reduction in antimicrobial use without increasing complication rates or length of hospital stay.
Disclosures
All Authors: No reported disclosures |
---|---|
AbstractList | Abstract
Background
Appropriate use of antibiotics is important for the prevention of antimicrobial-resistant organisms. However, prolonged administration of broad-spectrum antimicrobial agents is frequently used in surgery, especially in emergency surgery with infection. The low rate of the appropriate use of antimicrobial agents is regarded as a worldwide problem. In order to promote the proper use of antimicrobials, our department has administered daily antimicrobial time-outs to surgical patients as part of the Antimicrobial Stewardship Program since January 2018. This study investigates whether the Antimicrobial Time-out has led to appropriate use of antibiotics.
Methods
Patients aged 18 years and older who underwent emergency abdominal surgery in our department from May 2017 to August 2018 were included. Pre- and postoperative clinical information was extracted from the medical records.
Results
56 and 66 patients were treated before and after the introduction of antimicrobial time-out, respectively. The mean duration of antimicrobial use was 3.8 and 3.3 days before and after the introduction of antibiotic time-out. No significant difference was observed, but a 13.7% decrease was observed (P=0.51). Limiting the analysis to patients who received a minimum of two days of antimicrobial therapy, treated patients were 23 and 27, and the mean duration of antimicrobial use was 7.8 and 6.6 days(P=0.38) before and after the introduction of antibiotic time-out, respectively.
There were also no significant differences in the incidence of complications (Clavien-Dindo classification Grade II or higher) (28.6% vs. 25.8%, P=0.73) or length of hospital stay (17.2 vs. 14.0 days, P=0.38).
Conclusion
Antibiotic time-out in surgical practice may contribute to a reduction in antimicrobial use without increasing complication rates or length of hospital stay.
Disclosures
All Authors: No reported disclosures |
Author | Suenaga, Takahiro Hata, Hiroaki |
Author_xml | – sequence: 1 givenname: Takahiro surname: Suenaga fullname: Suenaga, Takahiro – sequence: 2 givenname: Hiroaki surname: Hata fullname: Hata, Hiroaki |
BookMark | eNqNUctOwzAQtFCRKKUfwM0fQIofSZMcq4qXVIkLnCPHXhejxo5sp1L5Oj4Np-0BiQuX3dXOzD4012hinQWEbilZUFLze6eNSkGogqQOJdUFmjLOqqyqi3Lyq75C8xA-CSGJVJCynqJvypbVAq-wh-hd6EFGswfs2gB-L6JxVuxwiIM64Ogw7MVuEBFw_AAMWhsp5AE7jYWNpjPSu9Ykfqohc0PE2nns-hH6MnZ7VKnBH8f-VQnVGWtCPOPGYujAb8GmFaJVLqHjLUNq-QPuEwtsDDfoUotdgPk5z9D748Pb-jnbvD69rFebTFKWvi-5qpVetqBaQqWiVQ6cF7Ks5LIVoqo4462GvGAlrSmvVa7qopCciZLlrVwyPkP0NDedG4IH3fTedMIfGkqa0YVmdKE5u9CMLiTN3Unjhv4f9B9I3JMO |
ContentType | Journal Article |
Copyright | The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. 2023 |
Copyright_xml | – notice: The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. 2023 |
DBID | TOX AAYXX CITATION |
DOI | 10.1093/ofid/ofad500.1108 |
DatabaseName | Oxford University Press Open Access CrossRef |
DatabaseTitle | CrossRef |
DatabaseTitleList | CrossRef |
Database_xml | – sequence: 1 dbid: TOX name: Oxford University Press Open Access url: https://academic.oup.com/journals/ sourceTypes: Publisher |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
DocumentTitleAlternate | IDWeek 2023 Abstracts |
EISSN | 2328-8957 |
ExternalDocumentID | 10_1093_ofid_ofad500_1108 10.1093/ofid/ofad500.1108 |
GroupedDBID | 0R~ 53G 5VS AAFWJ AAMVS AAPPN AAPXW AAVAP ABDBF ABPTD ABXVV ACGFS ADBBV ADHZD ADPDF ADRAZ AENZO AFPKN AFULF ALMA_UNASSIGNED_HOLDINGS ALUQC AOIJS BAWUL BAYMD BCNDV BTTYL CIDKT DIK EBS EJD GROUPED_DOAJ H13 HYE IAO KQ8 KSI M48 M~E O9- OAWHX OJQWA OK1 OVD OVEED PEELM ROL ROX RPM TEORI TJX TOX AAYXX CITATION ITC |
ID | FETCH-LOGICAL-c1228-73d9df6bedb01cd184e335c78c6baa88323bfe452719139d4d955c32a724bc623 |
IEDL.DBID | M48 |
ISSN | 2328-8957 |
IngestDate | Thu Sep 26 18:20:48 EDT 2024 Wed Aug 28 03:17:44 EDT 2024 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | Supplement_2 |
Language | English |
License | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c1228-73d9df6bedb01cd184e335c78c6baa88323bfe452719139d4d955c32a724bc623 |
OpenAccessLink | https://dx.doi.org/10.1093/ofid/ofad500.1108 |
ParticipantIDs | crossref_primary_10_1093_ofid_ofad500_1108 oup_primary_10_1093_ofid_ofad500_1108 |
PublicationCentury | 2000 |
PublicationDate | 2023-11-27 |
PublicationDateYYYYMMDD | 2023-11-27 |
PublicationDate_xml | – month: 11 year: 2023 text: 2023-11-27 day: 27 |
PublicationDecade | 2020 |
PublicationPlace | US |
PublicationPlace_xml | – name: US |
PublicationTitle | Open forum infectious diseases |
PublicationYear | 2023 |
Publisher | Oxford University Press |
Publisher_xml | – name: Oxford University Press |
SSID | ssj0001105079 |
Score | 2.3162596 |
Snippet | Abstract
Background
Appropriate use of antibiotics is important for the prevention of antimicrobial-resistant organisms. However, prolonged administration of... |
SourceID | crossref oup |
SourceType | Aggregation Database Publisher |
Title | 1268. A retrospective observational study to evaluate the efficacy of antimicrobial time-out for optimizing the duration of antimicrobial administration in emergency abdominal surgery patients |
Volume | 10 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3NS8MwFA9zgngRP3F-8Q56Eapt0zTtQUTEMYTpxcFuJWkSGOg6tw6cf51_mi9tKg4F8ZJL8nLILx-_l-T9HiGnSurIMMU9oVPqRUxpTwqW47oyxnAeR4GyF_r9h7g3iO6HbNgiTXorN4CzX107m09qMH2-eHtdXOOCv3JiSJeIgsJCKObX39pXyGpodbnsTz7H9qsrF-QSfqW-hzQi8ZKU8ead87delk4qG_327eDpbpINxxjhpoZ4i7T0eJus9d2b-A75CMI4uYAbmOpyWjSRk1DIr_tWtK5UZKEswKl7a0DiB9rqR4h8AYUBHOHRy6iSZcL2NuW8V8xLQE4LxcRWveMhV1mpeT1rflqJJSVeGI1BN9GdIKQqqgRiMKsjscFJus52yaB793Tb81xeBi8PQhw4TlWqTCy1kn6QK_QRNaUs50keSyES3COoNDpiIQ-s6KiKVMpYTkPBw0jmyLf2SHtcjPU-gRS9MSbTRPsSdw9fiIBTw9AnTKhU1KgOOW8wyCa1_EZWP5vTzAKWOcAyC1iHnCFKf7c7-E-nh2TdZpi34YchPyLtcjrXx8hDSnlS-e8n1RzD8ulx-AklReLI |
link.rule.ids | 315,783,787,867,1607,24332,27938,27939 |
linkProvider | Scholars Portal |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=1268.+A+retrospective+observational+study+to+evaluate+the+efficacy+of+antimicrobial+time-out+for+optimizing+the+duration+of+antimicrobial+administration+in+emergency+abdominal+surgery+patients&rft.jtitle=Open+forum+infectious+diseases&rft.au=Suenaga%2C+Takahiro&rft.au=Hata%2C+Hiroaki&rft.pub=Oxford+University+Press&rft.eissn=2328-8957&rft.volume=10&rft.issue=Supplement_2&rft_id=info:doi/10.1093%2Fofid%2Fofad500.1108&rft.externalDocID=10.1093%2Fofid%2Fofad500.1108 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2328-8957&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2328-8957&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2328-8957&client=summon |