Usefulness of K-ras mutational analysis as a routine method to increase diagnostic sensitivity of EUS-guided FNA

Aim: To explore if routine analysis for K-ras mutations increases sensitivity of EUS-guided FNA aspirates and determine the group of patients in which this could be useful. Results: 67 patients were included but 10 samples were not adequate for mutational analysis, so data on 57 patients is presente...

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Published inPancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] Vol. 17; no. 4; p. S25
Main Authors Ortega Espinosa, Cesar Ricardo, Sánchez del Monte, Julio, de la Mora Levy, José Guillermo, Alonso Larraga, Octavio, Ramírez Solís, Mauro Eduardo, Hernández Guerrero, Angélica
Format Journal Article
LanguageEnglish
Published Philadelphia Elsevier B.V 01.09.2017
Elsevier Limited
Subjects
Cellular biology
K-Ras protein
Medical diagnosis
Mutation
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Summary:Aim: To explore if routine analysis for K-ras mutations increases sensitivity of EUS-guided FNA aspirates and determine the group of patients in which this could be useful. Results: 67 patients were included but 10 samples were not adequate for mutational analysis, so data on 57 patients is presented, of which 28 were female with a mean age of 61 years (28-85).
ISSN:1424-3903
1424-3911
DOI:10.1016/j.pan.2017.07.084