Association between transient tachypnea of newborn and bronchiolitis development
Purpose: Transient tachypnea of newborn (TTN) is characterized by inadequate absorption of fetal lung fluid. While typically benign and self-limiting, TTN may be associated with an increased risk of wheezing syndromes. This study aimed to investigate the association between TTN and the development o...
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Published in | Allergy asthma & respiratory disease Vol. 13; no. 3; pp. 92 - 95 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
대한 소아알레르기 호흡기학회
01.07.2025
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Online Access | Get full text |
ISSN | 2288-0402 2288-0410 |
DOI | 10.4168/aard.2025.13.3.92 |
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Abstract | Purpose: Transient tachypnea of newborn (TTN) is characterized by inadequate absorption of fetal lung fluid. While typically benign and self-limiting, TTN may be associated with an increased risk of wheezing syndromes. This study aimed to investigate the association between TTN and the development of bronchiolitis within the first 2 years of life.
Methods: A retrospective cohort study included 184 newborns with TTN and 213 healthy controls, all born between January 1, 2006, and December 31, 2019. Medical records were analyzed for demographics, bronchiolitis incidence, and viral etiology.
Results: The incidence of bronchiolitis was significantly higher in the TTN group (29.3%) than in the healthy controls (14.1%) (P<0.01). TTN was identified as an independent risk factor for bronchiolitis (odds ratio, 2.44; 95% confidence interval, 1.45–4.11).
Conclusion: TTN may be a potential risk factor for bronchiolitis development. Further research is needed to clarify the possible association and underlying mechanisms linking TTN and bronchiolitis. KCI Citation Count: 0 |
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AbstractList | Purpose: Transient tachypnea of newborn (TTN) is characterized by inadequate absorption of fetal lung fluid. While typically benign and self-limiting, TTN may be associated with an increased risk of wheezing syndromes. This study aimed to investigate the association between TTN and the development of bronchiolitis within the first 2 years of life.
Methods: A retrospective cohort study included 184 newborns with TTN and 213 healthy controls, all born between January 1, 2006, and December 31, 2019. Medical records were analyzed for demographics, bronchiolitis incidence, and viral etiology.
Results: The incidence of bronchiolitis was significantly higher in the TTN group (29.3%) than in the healthy controls (14.1%) (P<0.01). TTN was identified as an independent risk factor for bronchiolitis (odds ratio, 2.44; 95% confidence interval, 1.45–4.11).
Conclusion: TTN may be a potential risk factor for bronchiolitis development. Further research is needed to clarify the possible association and underlying mechanisms linking TTN and bronchiolitis. KCI Citation Count: 0 |
Author | Brelopes, Sonia Alia Kang, Eun Kyeong |
Author_xml | – sequence: 1 givenname: Sonia Alia surname: Brelopes fullname: Brelopes, Sonia Alia organization: Department of Pediatrics, Guido Valadares National Hospital, Timor-Leste, East Timor – sequence: 2 givenname: Eun Kyeong orcidid: 0000-0003-4226-0700 surname: Kang fullname: Kang, Eun Kyeong organization: Department of Pediatrics, Dongguk University Medical Center, Goyang, Korea |
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