Structure–Activity Relationships and Therapeutic Potentials of 5-HT 7 Receptor Ligands: An Update

• Published in: Journal of medicinal chemistry Vol. 61; no. 19; pp. 8475 - 8503
• Main Authors: Modica, Maria N., Lacivita, Enza, Intagliata, Sebastiano, Salerno, Loredana, Romeo, Giuseppe, Pittalà, Valeria, Leopoldo, Marcello
• Format: Journal Article
• Language: English
• Published: United States 11.10.2018

Serotonin 5-HT receptor (5-HT R) has been the subject of intense research efforts because of its presence in brain areas such as the hippocampus, hypothalamus, and cortex. Preclinical data link the 5-HT R to a variety of central nervous system processes including the regulation of circadian rhythms,...