639. In Vivo Imaging of Lymph Node Metastasis with Telomerase-Specific Replication-Competent Adenovirus Containing Green Fluorescent Protein Gene

• Published in: Molecular therapy Vol. 13; no. S1; p. S246
• Main Authors: Kojima, Toru, Kishimoto, Hiroyuki, Watanabe, Yuichi, Kagawa, Shunsuke, Teraishi, Fuminori, Hioki, Masayoshi, Ikeda, Yoshihiro, Sakai, Ryo, Urata, Yasuo, Tanaka, Noriaki, Fujiwara, Toshiyoshi
• Format: Journal Article
• Language: English
• Published: Milwaukee Elsevier Limited 01.05.2006
• Subjects: Adenoviruses; Androgens; Cancer; Enzymes; Gene therapy; Infections; Lymphatic system; Metastasis; Prostate; Proteins; Telomerase; Tumors; Japan

Currently available methods for detection of tumors in vivo such as X-ray, computed tomography, ultrasonography, and magnetic resonance imaging are noninvasive and are well studied; the images, however, are not specific for tumors. Direct optical imaging of tumor cells in vivo that can clearly disti...