Microbubble Biointerfacing by Regulation of the Platelet Membrane Surfactant Activity at the Gas‐Liquid Interface for Acute Thrombosis Targeting

• Published in: Angewandte Chemie Vol. 136; no. 9
• Main Authors: Wang, Jiahui, Jin, Weikui, Huang, Shengyu, Wang, Wenqi, Wang, Siyu, Yu, Zhen, Gao, Li, Gao, Yu, Han, Hao, Wang, Lianhui
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley Subscription Services, Inc 26.02.2024
• Subjects: Cell membranes; Contrast agents; Contrast media; Fibrin; Lipids; Membrane vesicles; Membranes; Microbubble Biointerfacing; Nanomaterials; Nanoparticles; Nanotechnology; Phospholipids; Platelet Membranes; Platelets; Proteins; Surface tension; Surface Tension Regulation; Surfactants; Talin; Thromboembolism; Thrombosis; Ultrasonic imaging; Ultrasound; Ultrasound Theranostics

Biointerfacing nanomaterials with cell membranes has been successful in the functionalization of nanoparticles or nanovesicles, but microbubble functionalization remains challenging due to the unique conformation of the lipid monolayer structure at the gas‐liquid interface that provides insufficient...