EG-13 GENOME-WIDE METHYLATION ANALYSIS IDENTIFIES GENOMIC DNA DEMETHYLATION DURING MALIGNANT PROGRESSION OF GLIOMAS

• Published in: Neuro-oncology (Charlottesville, Va.) Vol. 16; no. suppl 5; p. v77
• Main Authors: Saito, K., Mukasa, A., Nagae, G., Aihara, K., Otani, R., Takayanagi, S., Omata, M., Tanaka, S., Shibahara, J., Takahashi, M., Momose, T., Shimamura, T., Miyano, S., Narita, Y., Ueki, K., Nishikawa, R., Nagane, M., Aburatani, H., Saito, N.
• Format: Journal Article
• Language: English
• Published: 01.11.2014

Low-grade gliomas often undergo malignant progression, and these transformations are a leading cause of death in patients with low-grade gliomas. However, the molecular mechanisms underlying malignant tumor progression are still not well understood. Recent evidence indicates that epigenetic deregula...