NMDA receptor and APOE in Alzheimer’s disease: searching for connections

Background NMDA receptor (NMDAR) malfunctioning has been claimed as a crucial event in Alzheimer’s disease (AD), the most common form of dementia. While synaptic NMDAR activation leads to synaptic plasticity, extrasynaptic NMDAR activation leads to excitotoxicity, mitotoxicity and cell death. In the...

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Bibliographic Details
Published inAlzheimer's & dementia Vol. 19; no. S1
Main Author Escamilla, Sergio
Format Journal Article
LanguageEnglish
Published 01.06.2023
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