Initial Evaluation of an Adenosine A 2A Receptor Ligand, 11 C-Preladenant, in Healthy Human Subjects - Sakata, Muneyuki; Ishibashi, Kenji; Imai, Masamichi; Wagatsuma, Kei; Ishii, Kenji; Zhou, Xiaoyun; de Vries, Erik F.J.; Elsinga, Philip H.; Ishiwata, Kiichi; Toyohara, Jun (Journal of Nuclear Medicine, 2017)
Keywords: Adult; Brain - diagnostic imaging; Brain - metabolism; Carbon Radioisotopes; Healthy Volunteers; Humans; Ligands; Male; Positron-Emission Tomography; Pyrimidines - adverse effects; Pyrimidines - metabolism; Pyrimidines - pharmacokinetics; Radiometry; Receptor, Adenosine A2A - metabolism; Safety; Tissue Distribution; Triazoles - adverse effects; Triazoles - metabolism; Triazoles - pharmacokinetics; Whole Body Imaging; Young Adult; human brain; 11C-preladenant; adenosine A2A receptor; positron emission tomography; radiation dosimetry