Expression of the rat liver carnitine palmitoyltransferase I (CPT-Iα) gene is regulated by Sp1 and nuclear factor Y: chromosomal localization and promoter characterization

• Published in: Biochemical journal Vol. 340; no. 2; pp. 425 - 432
• Main Authors: STEFFEN, Michelle L., HARRISON, Wilbur R., ELDER, Frederick F. B., COOK, George A., PARK, Edwards A.
• Format: Journal Article
• Language: English
• Published: 01.06.1999

Carnitine palmitoyltransferase (CPT)-I catalyses the transfer of long-chain fatty acids from CoA to carnitine for translocation across the mitochondrial inner membrane. Expression of the ‘liver’ isoform of the CPT-I gene (CPT-Iα) is subject to developmental, hormonal and tissue-specific regulation....