人体测量因素和Breslow厚度

Summary 黑色素瘤是挪威增长最快的癌症;2016年,2114名男性和女性被诊断为患该疾病。这种癌症通常能够在早期确诊,如果您密切关注皮肤的变化,将能够在早期检测出癌症。但是,转移性黑色素瘤(扩散到身体的其他部位)是一种难以治愈的严重疾病,挪威每年有超过300人死于黑色素瘤。肿瘤厚度(称为Breslow厚度)是患上黑色素瘤后能否存活的重要因素;诊断时肿瘤较薄的患者会比肿瘤较厚的患者生存时间更长。在挪威的一项新研究中,研究人员探索了某些因素(称为人体测量因素‐比如身体质量指数(BMI)、人体皮肤表面积(BSA)、身高、体重和体重变化)与Breslow厚度的整体关联,并按照解剖部位及组织学亚型...

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Published inBritish journal of dermatology (1951) Vol. 179; no. 3; p. e157
Main Authors Stenehjem, J.S., Veierød, M.B., Nilsen, L.T., Ghiasvand, R., Johnsen, B., Grimsrud, T.K., Babigumira, R., Støer, N.C., Rees, J.R., Robsahm, T.E.
Format Journal Article
LanguageEnglish
Published 01.09.2018
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Abstract Summary 黑色素瘤是挪威增长最快的癌症;2016年,2114名男性和女性被诊断为患该疾病。这种癌症通常能够在早期确诊,如果您密切关注皮肤的变化,将能够在早期检测出癌症。但是,转移性黑色素瘤(扩散到身体的其他部位)是一种难以治愈的严重疾病,挪威每年有超过300人死于黑色素瘤。肿瘤厚度(称为Breslow厚度)是患上黑色素瘤后能否存活的重要因素;诊断时肿瘤较薄的患者会比肿瘤较厚的患者生存时间更长。在挪威的一项新研究中,研究人员探索了某些因素(称为人体测量因素‐比如身体质量指数(BMI)、人体皮肤表面积(BSA)、身高、体重和体重变化)与Breslow厚度的整体关联,并按照解剖部位及组织学亚型(黑色素瘤类型)进行了分析。入选研究组(被称为基于Janus人口的1972–2003年群体)的近30万挪威男性和女性参加了黑色素瘤随访。到2014年,研究人员确定了2570例黑色素瘤的肿瘤厚度信息。这个大型黑色素瘤病例分析表明,BMI、BSA、体重和Breslow厚度之间存在正相关,这表明Breslow厚度随着BMI、BSA和体重的增加而增加,然后在达到最高值后趋于平稳或下降,这表示在最高值时出现行为或其他机制。 Linked Article: Stenehjem et al. Br J Dermatol 2018; 179:632–641
AbstractList Summary 黑色素瘤是挪威增长最快的癌症;2016年,2114名男性和女性被诊断为患该疾病。这种癌症通常能够在早期确诊,如果您密切关注皮肤的变化,将能够在早期检测出癌症。但是,转移性黑色素瘤(扩散到身体的其他部位)是一种难以治愈的严重疾病,挪威每年有超过300人死于黑色素瘤。肿瘤厚度(称为Breslow厚度)是患上黑色素瘤后能否存活的重要因素;诊断时肿瘤较薄的患者会比肿瘤较厚的患者生存时间更长。在挪威的一项新研究中,研究人员探索了某些因素(称为人体测量因素‐比如身体质量指数(BMI)、人体皮肤表面积(BSA)、身高、体重和体重变化)与Breslow厚度的整体关联,并按照解剖部位及组织学亚型(黑色素瘤类型)进行了分析。入选研究组(被称为基于Janus人口的1972–2003年群体)的近30万挪威男性和女性参加了黑色素瘤随访。到2014年,研究人员确定了2570例黑色素瘤的肿瘤厚度信息。这个大型黑色素瘤病例分析表明,BMI、BSA、体重和Breslow厚度之间存在正相关,这表明Breslow厚度随着BMI、BSA和体重的增加而增加,然后在达到最高值后趋于平稳或下降,这表示在最高值时出现行为或其他机制。 Linked Article: Stenehjem et al. Br J Dermatol 2018; 179:632–641
Author Stenehjem, J.S.
Støer, N.C.
Rees, J.R.
Babigumira, R.
Robsahm, T.E.
Ghiasvand, R.
Grimsrud, T.K.
Johnsen, B.
Veierød, M.B.
Nilsen, L.T.
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