Discovery of α-Substituted Imidazole-4-acetic Acid Analogues as a Novel Class of ρ 1 γ-Aminobutyric Acid Type A Receptor Antagonists with Effect on Retinal Vascular Tone
The ρ-containing γ-aminobutyric acid type A receptors (GABA Rs) play an important role in controlling visual signaling. Therefore, ligands that selectively target these GABA Rs are of interest. In this study, we demonstrate that the partial GABA R agonist imidazole-4-acetic acid (IAA) is able to pen...
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Published in | ChemMedChem Vol. 11; no. 20; pp. 2299 - 2310 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Germany
19.10.2016
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Subjects | |
Online Access | Get full text |
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